Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64816
MIM: 606534
HGNC: 17450
Ensembl: ENSG00000021461
Variants:
dbSNP: 64816
ClinVar: 64816
TCGA: ENSG00000021461
COSMIC: CYP3A43
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA165108401 | Acute coronary syndrome | Disease | ClinicalAnnotation | associated | PK | 25935875 | |
| PA165374673 | ticagrelor | Chemical | ClinicalAnnotation | associated | PK | 25935875 | |
| PA447216 | Schizophrenia | Disease | ClinicalAnnotation | associated | PK | PD | 21519338, 24595013 |
| PA450688 | olanzapine | Chemical | ClinicalAnnotation | associated | PK | PD | 21519338, 24595013 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36613552 | 2022 | Effects of CYP3A43 Expression on Cell Proliferation and Migration of Lung Adenocarcinoma and Its Clinical Significance. | 4 |
| 36613552 | 2022 | Effects of CYP3A43 Expression on Cell Proliferation and Migration of Lung Adenocarcinoma and Its Clinical Significance. | 4 |
| 32301865 | 2020 | Cis-acting regulatory elements regulating CYP3A4 transcription in human liver. | 7 |
| 32301865 | 2020 | Cis-acting regulatory elements regulating CYP3A4 transcription in human liver. | 7 |
| 28673024 | 2018 | Ancestry-Adjusted Vitamin D Metabolite Concentrations in Association With Cytochrome P450 3A Polymorphisms. | 3 |
| 28673024 | 2018 | Ancestry-Adjusted Vitamin D Metabolite Concentrations in Association With Cytochrome P450 3A Polymorphisms. | 3 |
| 26585945 | 2016 | Searching for candidate genes in familial BRCAX mutation carriers with prostate cancer. | 5 |
| 26585945 | 2016 | Searching for candidate genes in familial BRCAX mutation carriers with prostate cancer. | 5 |
| 25150845 | 2015 | Genetic variation in CYP3A43 is associated with response to antipsychotic medication. | 14 |
| 25150845 | 2015 | Genetic variation in CYP3A43 is associated with response to antipsychotic medication. | 14 |
| 24595013 | 2014 | No influence of CYP3A43 rs472660G> A on steady-state serum olanzapine concentrations in white psychiatric patients. | 1 |
| 24595013 | 2014 | No influence of CYP3A43 rs472660G> A on steady-state serum olanzapine concentrations in white psychiatric patients. | 1 |
| 20529763 | 2010 | Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE. | 8 |
| 20715157 | 2010 | The frameshift polymorphism CYP3A43_74_delA is associated with poor differentiation of breast tumors. | 3 |
| 21081028 | 2010 | Genetic variations in androgen metabolism genes and associations with prostate cancer in South African men. | 7 |
Citation
Dessen P
CYP3A43 (cytochrome P450 family 3 subfamily A member 43)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43751/cyp3a43
