Identity
HGNC
LOCATION
4q23
LOCUSID
ALIAS
ADH-3,ADHX,AMEDS,BMFS7,FALDH,FDH,GSH-FDH,GSNOR,HEL-S-60p
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 128
MIM: 103710
HGNC: 253
Ensembl: ENSG00000197894
Variants:
dbSNP: 128
ClinVar: 128
TCGA: ENSG00000197894
COSMIC: ADH5
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36656716 | 2023 | GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation. | 1 |
| 37615925 | 2023 | Effects of the major formaldehyde catalyzer ADH5 on phenotypes of fanconi anemia zebrafish model. | 0 |
| 36656716 | 2023 | GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation. | 1 |
| 37615925 | 2023 | Effects of the major formaldehyde catalyzer ADH5 on phenotypes of fanconi anemia zebrafish model. | 0 |
| 33512438 | 2021 | Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency. | 10 |
| 34219079 | 2021 | [Aldehyde degradation deficiency (ADD) syndrome: discovery of a novel fanconi anemia-like inherited BMF syndrome due to combined ADH5/ALDH2 deficiency]. | 1 |
| 33512438 | 2021 | Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency. | 10 |
| 34219079 | 2021 | [Aldehyde degradation deficiency (ADD) syndrome: discovery of a novel fanconi anemia-like inherited BMF syndrome due to combined ADH5/ALDH2 deficiency]. | 1 |
| 32112881 | 2020 | Mitophagy contributes to alpha-tocopheryl succinate toxicity in GSNOR-deficient hepatocellular carcinoma. | 6 |
| 33147438 | 2020 | Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans. | 47 |
| 32112881 | 2020 | Mitophagy contributes to alpha-tocopheryl succinate toxicity in GSNOR-deficient hepatocellular carcinoma. | 6 |
| 33147438 | 2020 | Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans. | 47 |
| 31043586 | 2019 | nNOS/GSNOR interaction contributes to skeletal muscle differentiation and homeostasis. | 5 |
| 31043586 | 2019 | nNOS/GSNOR interaction contributes to skeletal muscle differentiation and homeostasis. | 5 |
| 29074597 | 2018 | S-Nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating Autophagy. | 33 |
Citation
Dessen P
ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43755/adh5
