Identity
HGNC
LOCATION
20q11.22
LOCUSID
ALIAS
CAB,EIF3A,ITGB4BP,b(2)gcn,eIF-6,p27(BBP),p27BBP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3692
MIM: 602912
HGNC: 6159
Ensembl: ENSG00000242372
Variants:
dbSNP: 3692
ClinVar: 3692
TCGA: ENSG00000242372
COSMIC: EIF6
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Ribosome biogenesis in eukaryotes | KEGG | ko03008 |
| Ribosome biogenesis in eukaryotes | KEGG | hsa03008 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36651285 | 2023 | Dynamic states of eIF6 and SDS variants modulate interactions with uL14 of the 60S ribosomal subunit. | 1 |
| 37776372 | 2023 | Circular RNA eukaryotic translation initiation factor 6 facilitates TPC-1 cell proliferation and invasion through the microRNA-138-5p/lipase H axis. | 0 |
| 36651285 | 2023 | Dynamic states of eIF6 and SDS variants modulate interactions with uL14 of the 60S ribosomal subunit. | 1 |
| 37776372 | 2023 | Circular RNA eukaryotic translation initiation factor 6 facilitates TPC-1 cell proliferation and invasion through the microRNA-138-5p/lipase H axis. | 0 |
| 35024764 | 2022 | Eukaryotic initiation factor 6 regulates mechanical responses in endothelial cells. | 5 |
| 35887068 | 2022 | Inhibition of eIF6 Activity Reduces Hepatocellular Carcinoma Growth: An In Vivo and In Vitro Study. | 4 |
| 35024764 | 2022 | Eukaryotic initiation factor 6 regulates mechanical responses in endothelial cells. | 5 |
| 35887068 | 2022 | Inhibition of eIF6 Activity Reduces Hepatocellular Carcinoma Growth: An In Vivo and In Vitro Study. | 4 |
| 34016142 | 2021 | eIF6 promotes the malignant progression of human hepatocellular carcinoma via the mTOR signaling pathway. | 11 |
| 34385447 | 2021 | Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma. | 14 |
| 34403101 | 2021 | Roles of HDAC2, eIF5, and eIF6 in Lung Cancer Tumorigenesis. | 6 |
| 34413298 | 2021 | Somatic genetic rescue of a germline ribosome assembly defect. | 26 |
| 34016142 | 2021 | eIF6 promotes the malignant progression of human hepatocellular carcinoma via the mTOR signaling pathway. | 11 |
| 34385447 | 2021 | Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma. | 14 |
| 34403101 | 2021 | Roles of HDAC2, eIF5, and eIF6 in Lung Cancer Tumorigenesis. | 6 |
Citation
Dessen P
EIF6 (eukaryotic translation initiation factor 6)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43756/eif6
