Identity
HGNC
LOCATION
9q21.13
LOCUSID
ALIAS
C2GNT,C2GNT-L,C2GNT1,G6NT,NACGT2,NAGCT2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2650
MIM: 600391
HGNC: 4203
Ensembl: ENSG00000187210
Variants:
dbSNP: 2650
ClinVar: 2650
TCGA: ENSG00000187210
COSMIC: GCNT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000187210 | ENST00000376730 | Q02742 |
| ENSG00000187210 | ENST00000442371 | Q02742 |
| ENSG00000187210 | ENST00000444201 | Q02742 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37813880 | 2023 | The role of GCNT1 mediated O-glycosylation in aggressive prostate cancer. | 2 |
| 37813880 | 2023 | The role of GCNT1 mediated O-glycosylation in aggressive prostate cancer. | 2 |
| 26768364 | 2016 | Core 2 β-1, 6-N-acetylglucosaminyltransferase-1 expression in prostate biopsy specimen is an indicator of prostate cancer aggressiveness. | 15 |
| 26768364 | 2016 | Core 2 β-1, 6-N-acetylglucosaminyltransferase-1 expression in prostate biopsy specimen is an indicator of prostate cancer aggressiveness. | 15 |
| 26390303 | 2015 | Detection of Core2 β-1,6-N-Acetylglucosaminyltransferase in Post-Digital Rectal Examination Urine Is a Reliable Indicator for Extracapsular Extension of Prostate Cancer. | 13 |
| 26390303 | 2015 | Detection of Core2 β-1,6-N-Acetylglucosaminyltransferase in Post-Digital Rectal Examination Urine Is a Reliable Indicator for Extracapsular Extension of Prostate Cancer. | 13 |
| 23990450 | 2014 | Golgi fragmentation induced by heat shock or inhibition of heat shock proteins is mediated by non-muscle myosin IIA via its interaction with glycosyltransferases. | 19 |
| 24854630 | 2014 | Increased expression of GCNT1 is associated with altered O-glycosylation of PSA, PAP, and MUC1 in human prostate cancers. | 32 |
| 25086069 | 2014 | Restoration of compact Golgi morphology in advanced prostate cancer enhances susceptibility to galectin-1-induced apoptosis by modifying mucin O-glycan synthesis. | 42 |
| 23990450 | 2014 | Golgi fragmentation induced by heat shock or inhibition of heat shock proteins is mediated by non-muscle myosin IIA via its interaction with glycosyltransferases. | 19 |
| 24854630 | 2014 | Increased expression of GCNT1 is associated with altered O-glycosylation of PSA, PAP, and MUC1 in human prostate cancers. | 32 |
| 25086069 | 2014 | Restoration of compact Golgi morphology in advanced prostate cancer enhances susceptibility to galectin-1-induced apoptosis by modifying mucin O-glycan synthesis. | 42 |
| 23165940 | 2013 | Core2 O-glycan-expressing prostate cancer cells are resistant to NK cell immunity. | 29 |
| 23617619 | 2013 | Immunohistochemical expression of core 2 β1,6-N-acetylglucosaminyl transferase 1 (C2GnT1) in endometrioid-type endometrial carcinoma: a novel potential prognostic factor. | 10 |
| 23165940 | 2013 | Core2 O-glycan-expressing prostate cancer cells are resistant to NK cell immunity. | 29 |
Citation
Dessen P
GCNT1 (glucosaminyl (N-acetyl) transferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43762/gcnt1
