Identity
HGNC
LOCATION
2p13.1
LOCUSID
ALIAS
2010002K04Rik,NSPC1,RNF3A-2,RNF68
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84759
MIM: 610231
HGNC: 17615
Ensembl: ENSG00000115289
Variants:
dbSNP: 84759
ClinVar: 84759
TCGA: ENSG00000115289
COSMIC: PCGF1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115289 | ENST00000233630 | Q9BSM1 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signaling pathways regulating pluripotency of stem cells | KEGG | hsa04550 |
| Signaling pathways regulating pluripotency of stem cells | KEGG | ko04550 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38088808 | 2024 | Balanced Epigenetic Regulation of MHC Class I Expression in Tumor Cells by the Histone Ubiquitin Modifiers BAP1 and PCGF1. | 0 |
| 38088808 | 2024 | Balanced Epigenetic Regulation of MHC Class I Expression in Tumor Cells by the Histone Ubiquitin Modifiers BAP1 and PCGF1. | 0 |
| 36815373 | 2023 | Cooperation between NSPc1 and DNA methylation represses HOXA11 expression and promotes apoptosis of trophoblast cells during preeclampsia. | 0 |
| 36932196 | 2023 | MORC4 plays a tumor-promoting role in colorectal cancer via regulating PCGF1/CDKN1A axis in vitro and in vivo. | 1 |
| 36815373 | 2023 | Cooperation between NSPc1 and DNA methylation represses HOXA11 expression and promotes apoptosis of trophoblast cells during preeclampsia. | 0 |
| 36932196 | 2023 | MORC4 plays a tumor-promoting role in colorectal cancer via regulating PCGF1/CDKN1A axis in vitro and in vivo. | 1 |
| 34148069 | 2021 | PCGF1 promotes epigenetic activation of stemness markers and colorectal cancer stem cell enrichment. | 14 |
| 34148069 | 2021 | PCGF1 promotes epigenetic activation of stemness markers and colorectal cancer stem cell enrichment. | 14 |
| 32628469 | 2020 | Structure and Role of BCOR PUFD in Noncanonical PRC1 Assembly and Disease. | 5 |
| 32628469 | 2020 | Structure and Role of BCOR PUFD in Noncanonical PRC1 Assembly and Disease. | 5 |
| 28394339 | 2017 | NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma. | 28 |
| 28849208 | 2017 | MicroRNA‑320a inhibition decreases insulin‑induced KGN cell proliferation and apoptosis by targeting PCGF1. | 5 |
| 28394339 | 2017 | NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma. | 28 |
| 28849208 | 2017 | MicroRNA‑320a inhibition decreases insulin‑induced KGN cell proliferation and apoptosis by targeting PCGF1. | 5 |
| 26687479 | 2015 | The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis. | 27 |
Citation
Dessen P
PCGF1 (polycomb group ring finger 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43770/pcgf1
