PGC (progastricsin)

2007-02-01  

Identity

HGNC
PGC
LOCATION
6p21.1
LOCUSID
5225
ALIAS
PEPC,PGII
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5225
MIM: 169740
HGNC: 8890
Ensembl: ENSG00000096088

Variants:

dbSNP: 5225
ClinVar: 5225
TCGA: ENSG00000096088
COSMIC: PGC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000096088ENST00000356667Q4VXA6
ENSG00000096088ENST00000373025P20142
ENSG00000096088ENST00000415707A2A3L9
ENSG00000096088ENST00000425343P20142

Expression (GTEx)

0
5000
10000
15000
20000
25000
30000
35000
40000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
370388002023Medium and large alleles of the PGC gene are risk factors for gastric cancer.0
370388002023Medium and large alleles of the PGC gene are risk factors for gastric cancer.0
349979892022Pepsinogen II in gastritis and Helicobacter pylori infection.3
349979892022Pepsinogen II in gastritis and Helicobacter pylori infection.3
331272502021Association between serum pepsinogen and atherosclerotic cardiovascular disease.1
344638922021Pepsinogen C expression-related lncRNA/circRNA/mRNA profile and its co-mediated ceRNA network in gastric cancer.5
348173332021Diagnostic value of MRI-DWI signal intensity value combined with serum PGI, PGII and CA199 in early gastric cancer.2
331272502021Association between serum pepsinogen and atherosclerotic cardiovascular disease.1
344638922021Pepsinogen C expression-related lncRNA/circRNA/mRNA profile and its co-mediated ceRNA network in gastric cancer.5
348173332021Diagnostic value of MRI-DWI signal intensity value combined with serum PGI, PGII and CA199 in early gastric cancer.2
304006792020Clinical correlation between serum pepsinogen level and gastric atrophy in gastric neoplasm.12
322283422020Diagnostic value of serum pepsinogen I, pepsinogen II, and gastrin-17 levels for population-based screening for early-stage gastric cancer.9
322717652020Serum pepsinogens as a gastric cancer and gastritis biomarker in South and Southeast Asian populations.8
304006792020Clinical correlation between serum pepsinogen level and gastric atrophy in gastric neoplasm.12
322283422020Diagnostic value of serum pepsinogen I, pepsinogen II, and gastrin-17 levels for population-based screening for early-stage gastric cancer.9

Citation

Dessen P

PGC (progastricsin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43776