KIR3DL2 (killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2)

2007-02-01  

Identity

HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
3DL2,CD158K,KIR-3DL2,NKAT-4,NKAT4,NKAT4B,p140

Other Information

Locus ID:

NCBI: 3812
MIM: 604947
HGNC: 6339
Ensembl: ENSG00000240403

Variants:

dbSNP: 3812
ClinVar: 3812
TCGA: ENSG00000240403
COSMIC: KIR3DL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000240403ENST00000270442P43630
ENSG00000240403ENST00000326321P43630
ENSG00000240403ENST00000326321A0A0U1WNF3

Expression (GTEx)

0
1
2
3
4

Pathways

PathwaySourceExternal ID
Antigen processing and presentationKEGGko04612
Natural killer cell mediated cytotoxicityKEGGko04650
Graft-versus-host diseaseKEGGko05332
Antigen processing and presentationKEGGhsa04612
Natural killer cell mediated cytotoxicityKEGGhsa04650
Graft-versus-host diseaseKEGGhsa05332
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

References

Pubmed IDYearTitleCitations
382628742024Activating KIR/HLA-I combinations as a risk factor of adult B-ALL.0
382628742024Activating KIR/HLA-I combinations as a risk factor of adult B-ALL.0
345702002022CD158k and PD-1 expressions define heterogeneous subtypes of Sezary syndrome.5
345702002022CD158k and PD-1 expressions define heterogeneous subtypes of Sezary syndrome.5
340960332021[Study of the distribution of KIR3DL2 alleles among ethnic Han Chinese from Zhejiang].0
340960332021[Study of the distribution of KIR3DL2 alleles among ethnic Han Chinese from Zhejiang].0
293154922018KIR3DL2 expression in patients with adult T-cell lymphoma/leukaemia.3
293154922018KIR3DL2 expression in patients with adult T-cell lymphoma/leukaemia.3
281193652017Usefulness of KIR3DL2 to Diagnose, Follow-Up, and Manage the Treatment of Patients with Sézary Syndrome.13
290893102017KIR3DL2 expression in cutaneous T-cell lymphomas: expanding the spectrum for KIR3DL2 targeting.11
281193652017Usefulness of KIR3DL2 to Diagnose, Follow-Up, and Manage the Treatment of Patients with Sézary Syndrome.13
290893102017KIR3DL2 expression in cutaneous T-cell lymphomas: expanding the spectrum for KIR3DL2 targeting.11
268413532016Activation-Induced Killer Cell Immunoglobulin-like Receptor 3DL2 Binding to HLA-B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis.21
269284642016Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis.64
268413532016Activation-Induced Killer Cell Immunoglobulin-like Receptor 3DL2 Binding to HLA-B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis.21

Citation

Dessen P

KIR3DL2 (killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43782/kir3dl2