KLF8 (Kruppel like factor 8)

2007-02-01  

Identity

HGNC
KLF8
LOCATION
Xp11.21
LOCUSID
11279
ALIAS
BKLF3,ZNF741

Other Information

Locus ID:

NCBI: 11279
MIM: 300286
HGNC: 6351
Ensembl: ENSG00000102349

Variants:

dbSNP: 11279
ClinVar: 11279
TCGA: ENSG00000102349
COSMIC: KLF8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102349ENST00000358094Q05BZ3
ENSG00000102349ENST00000374928O95600
ENSG00000102349ENST00000468660O95600
ENSG00000102349ENST00000468660A0A024R9X4
ENSG00000102349ENST00000640927O95600

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
382878042024KLF8 Promotes the Survival of Lung Adenocarcinoma During Nutrient Deprivation by Regulating the Pentose Phosphate Pathway through SIRT2.0
382878042024KLF8 Promotes the Survival of Lung Adenocarcinoma During Nutrient Deprivation by Regulating the Pentose Phosphate Pathway through SIRT2.0
350317882022Oncogenic E3 ubiquitin ligase NEDD4 binds to KLF8 and regulates the microRNA-132/NRF2 axis in bladder cancer.10
351713592022CircRNA PVT1 promotes proliferation and chemoresistance of osteosarcoma cells via the miR-24-3p/KLF8 axis.7
352930142022KLF8 is activated by TGF-β1 via Smad2 and contributes to ovarian cancer progression.7
350317882022Oncogenic E3 ubiquitin ligase NEDD4 binds to KLF8 and regulates the microRNA-132/NRF2 axis in bladder cancer.10
351713592022CircRNA PVT1 promotes proliferation and chemoresistance of osteosarcoma cells via the miR-24-3p/KLF8 axis.7
352930142022KLF8 is activated by TGF-β1 via Smad2 and contributes to ovarian cancer progression.7
321221442020KLF8 promotes cancer stem cell-like phenotypes in osteosarcoma through miR-429-SOX2 signaling.10
324117962020miR-24-3p/KLF8 Signaling Axis Contributes to LUAD Metastasis by Regulating EMT.7
327689512020Circ_0067934 promotes non-small cell lung cancer development by regulating miR-1182/KLF8 axis and activating Wnt/β-catenin pathway.21
321221442020KLF8 promotes cancer stem cell-like phenotypes in osteosarcoma through miR-429-SOX2 signaling.10
324117962020miR-24-3p/KLF8 Signaling Axis Contributes to LUAD Metastasis by Regulating EMT.7
327689512020Circ_0067934 promotes non-small cell lung cancer development by regulating miR-1182/KLF8 axis and activating Wnt/β-catenin pathway.21
289867412019Krüppel-Like Factor 8 Overexpression Correlates with Poor Prognosis in Non-Small Cell Lung Cancer.8

Citation

Dessen P

KLF8 (Kruppel like factor 8)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43804