Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3738
MIM: 176263
HGNC: 6221
Ensembl: ENSG00000177272
Variants:
dbSNP: 3738
ClinVar: 3738
TCGA: ENSG00000177272
COSMIC: KCNA3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000177272 | ENST00000369769 | P22001 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuronal System | REACTOME | R-HSA-112316 |
| Potassium Channels | REACTOME | R-HSA-1296071 |
| Voltage gated Potassium channels | REACTOME | R-HSA-1296072 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37964487 | 2024 | De novo variants in KCNA3 cause developmental and epileptic encephalopathy. | 1 |
| 38542732 | 2024 | Effect of the rs2821557 Polymorphism of the Human Kv1.3 Gene on Olfactory Function and BMI in Different Age Groups. | 0 |
| 37964487 | 2024 | De novo variants in KCNA3 cause developmental and epileptic encephalopathy. | 1 |
| 38542732 | 2024 | Effect of the rs2821557 Polymorphism of the Human Kv1.3 Gene on Olfactory Function and BMI in Different Age Groups. | 0 |
| 35091471 | 2022 | Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug. | 13 |
| 35328733 | 2022 | Role of C-Terminal Domain and Membrane Potential in the Mobility of Kv1.3 Channels in Immune Synapse Forming T Cells. | 0 |
| 35788586 | 2022 | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. | 21 |
| 36501016 | 2022 | Olfactory Sensitivity Is Associated with Body Mass Index and Polymorphism in the Voltage-Gated Potassium Channels Kv1.3. | 4 |
| 35091471 | 2022 | Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug. | 13 |
| 35328733 | 2022 | Role of C-Terminal Domain and Membrane Potential in the Mobility of Kv1.3 Channels in Immune Synapse Forming T Cells. | 0 |
| 35788586 | 2022 | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. | 21 |
| 36501016 | 2022 | Olfactory Sensitivity Is Associated with Body Mass Index and Polymorphism in the Voltage-Gated Potassium Channels Kv1.3. | 4 |
| 32056271 | 2021 | A common genetic variant rs2821557 in KCNA3 is linked to the severity of multiple sclerosis. | 3 |
| 32910509 | 2021 | The Kv1.3 ion channel acts as a host factor restricting viral entry. | 0 |
| 33230847 | 2021 | Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation. | 5 |
Citation
Dessen P
KCNA3 (potassium voltage-gated channel subfamily A member 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43811/kcna3
