Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1671
MIM: 600471
HGNC: 2765
Ensembl: ENSG00000164822
Variants:
dbSNP: 1671
ClinVar: 1671
TCGA: ENSG00000164822
COSMIC: DEFA6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164822 | ENST00000297436 | Q01524 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35562899 | 2022 | Human α-Defensin-6 Neutralizes Clostridioides difficile Toxins TcdA and TcdB by Direct Binding. | 3 |
| 35562899 | 2022 | Human α-Defensin-6 Neutralizes Clostridioides difficile Toxins TcdA and TcdB by Direct Binding. | 3 |
| 32089753 | 2020 | Upregulated Expression of Intestinal Antimicrobial Peptide HD5 Associated with Renal Function in IgA Nephropathy. | 1 |
| 32089753 | 2020 | Upregulated Expression of Intestinal Antimicrobial Peptide HD5 Associated with Renal Function in IgA Nephropathy. | 1 |
| 30808760 | 2019 | Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments. | 47 |
| 30932884 | 2019 | Defensin alpha 6 (DEFA6) is a prognostic marker in colorectal cancer. | 10 |
| 30808760 | 2019 | Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments. | 47 |
| 30932884 | 2019 | Defensin alpha 6 (DEFA6) is a prognostic marker in colorectal cancer. | 10 |
| 28026958 | 2017 | Human α-Defensin 6 Self-Assembly Prevents Adhesion and Suppresses Virulence Traits of Candida albicans. | 16 |
| 28198610 | 2017 | Disentangling Nanonets: Human α-Defensin 6 Targets Candida albicans Virulence. | 1 |
| 28026958 | 2017 | Human α-Defensin 6 Self-Assembly Prevents Adhesion and Suppresses Virulence Traits of Candida albicans. | 16 |
| 28198610 | 2017 | Disentangling Nanonets: Human α-Defensin 6 Targets Candida albicans Virulence. | 1 |
| 26891258 | 2016 | Reduced Human α-defensin 6 in Noninflamed Jejunal Tissue of Patients with Crohn's Disease. | 10 |
| 26891258 | 2016 | Reduced Human α-defensin 6 in Noninflamed Jejunal Tissue of Patients with Crohn's Disease. | 10 |
| 25354318 | 2015 | Paneth cell α-defensin 6 (HD-6) is an antimicrobial peptide. | 51 |
Citation
Dessen P
DEFA6 (defensin alpha 6)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43817/defa6
