KIF11 (kinesin family member 11)

2007-02-01  

Identity

HGNC
LOCATION
10q23.33
LOCUSID
ALIAS
EG5,HKSP,KNSL1,MCLMR,TRIP5
FUSION GENES

Other Information

Locus ID:

NCBI: 3832
MIM: 148760
HGNC: 6388
Ensembl: ENSG00000138160

Variants:

dbSNP: 3832
ClinVar: 3832
TCGA: ENSG00000138160
COSMIC: KIF11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138160ENST00000260731P52732

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
MHC class II antigen presentationREACTOMER-HSA-2132295
HemostasisREACTOMER-HSA-109582
Factors involved in megakaryocyte development and platelet productionREACTOMER-HSA-983231
KinesinsREACTOMER-HSA-983189
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-dependent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811434

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
384242392024Human kinesin-5 KIF11 drives the helical motion of anti-parallel and parallel microtubules around each other.1
386724042024Mitotic Functions and Characters of KIF11 in Cancers.0
384242392024Human kinesin-5 KIF11 drives the helical motion of anti-parallel and parallel microtubules around each other.1
386724042024Mitotic Functions and Characters of KIF11 in Cancers.0
368839092023ASPM promotes migration and invasion of anaplastic thyroid carcinoma by stabilizing KIF11.4
376562432023KIF11 serves as a cell cycle mediator in childhood acute lymphoblastic leukemia.1
377286572023UHRF1 promotes spindle assembly and chromosome congression by catalyzing EG5 polyubiquitination.4
368839092023ASPM promotes migration and invasion of anaplastic thyroid carcinoma by stabilizing KIF11.4
376562432023KIF11 serves as a cell cycle mediator in childhood acute lymphoblastic leukemia.1
377286572023UHRF1 promotes spindle assembly and chromosome congression by catalyzing EG5 polyubiquitination.4
334911542022Upregulation of KIF11 in TP53 Mutant Glioma Promotes Tumor Stemness and Drug Resistance.10
335547612022High KIF11 expression is associated with poor outcome of NSCLC.6
343784812022KIF11 as a potential cancer prognostic marker promotes tumorigenesis in children with Wilms tumor.1
345827652022Severe Exudative Vitreoretinopathy as a Common Feature for CTNNB1, KIF11 and NDP Variants Plus Sector Degeneration for KIF11.3
348007192022KIF11, a plus end-directed kinesin, as a key gene in benzo(a)pyrene-induced non-small cell lung cancer.5

Citation

Dessen P

KIF11 (kinesin family member 11)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43858/kif11