Identity
HGNC
LOCATION
16p12.1
LOCUSID
ALIAS
CD124,IL-4RA,IL4RA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3566
MIM: 147781
HGNC: 6015
Ensembl: ENSG00000077238
Variants:
dbSNP: 3566
ClinVar: 3566
TCGA: ENSG00000077238
COSMIC: IL4R
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164712789 | Hepatitis vaccines | Chemical | ClinicalAnnotation | associated | PD | 21111021 | |
| PA165983754 | pitrakinra | Chemical | ClinicalAnnotation | associated | PD | ||
| PA443450 | Asthma | Disease | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37933466 | 2024 | Th2 cytokine signaling through IL-4Rα increases eotaxin-3 secretion and tension in human esophageal smooth muscle. | 0 |
| 38426866 | 2024 | Global IL4Rα blockade exacerbates heart failure after an ischemic event in mice and humans. | 0 |
| 38731867 | 2024 | Type II Interleukin-4 Receptor Activation in Basal Breast Cancer Cells Promotes Tumor Progression via Metabolic and Epigenetic Modulation. | 0 |
| 37933466 | 2024 | Th2 cytokine signaling through IL-4Rα increases eotaxin-3 secretion and tension in human esophageal smooth muscle. | 0 |
| 38426866 | 2024 | Global IL4Rα blockade exacerbates heart failure after an ischemic event in mice and humans. | 0 |
| 38731867 | 2024 | Type II Interleukin-4 Receptor Activation in Basal Breast Cancer Cells Promotes Tumor Progression via Metabolic and Epigenetic Modulation. | 0 |
| 36070083 | 2023 | Epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis. | 9 |
| 36445014 | 2023 | IgG memory B cells expressing IL4R and FCER2 are associated with atopic diseases. | 5 |
| 37117331 | 2023 | Prognosis value and positive association of Rab1A/IL4Rα aberrant expression in gastric cancer. | 0 |
| 37551548 | 2023 | Association of IL4RA polymorphism in predicting susceptibility toward chronic obstructive pulmonary disease. | 0 |
| 36070083 | 2023 | Epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis. | 9 |
| 36445014 | 2023 | IgG memory B cells expressing IL4R and FCER2 are associated with atopic diseases. | 5 |
| 37117331 | 2023 | Prognosis value and positive association of Rab1A/IL4Rα aberrant expression in gastric cancer. | 0 |
| 37551548 | 2023 | Association of IL4RA polymorphism in predicting susceptibility toward chronic obstructive pulmonary disease. | 0 |
| 35589010 | 2022 | Atopic Dermatitis Mediates the Association Between an IL4RA Variant and Food Allergy in School-Aged Children. | 3 |
Citation
Dessen P
IL4R (interleukin 4 receptor)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43873/il4r
