OGFR (opioid growth factor receptor)

2007-02-01  

Identity

HGNC
OGFR
LOCATION
20q13.33
LOCUSID
11054
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 11054
MIM: 606459
HGNC: 15768
Ensembl: ENSG00000060491

Variants:

dbSNP: 11054
ClinVar: 11054
TCGA: ENSG00000060491
COSMIC: OGFR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000060491ENST00000290291Q9NZT2
ENSG00000060491ENST00000370461A0A0A0MRN5
ENSG00000060491ENST00000450048Q4VXW3
ENSG00000060491ENST00000621591A0A087X028

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
336774092021β-endorphin and opioid growth factor as biomarkers of physical ability in multiple sclerosis.2
336774092021β-endorphin and opioid growth factor as biomarkers of physical ability in multiple sclerosis.2
271676862016Morphine Suppresses Lung Cancer Cell Proliferation Through the Interaction with Opioid Growth Factor Receptor: An In Vitro and Human Lung Tissue Study.26
271676862016Morphine Suppresses Lung Cancer Cell Proliferation Through the Interaction with Opioid Growth Factor Receptor: An In Vitro and Human Lung Tissue Study.26
258538622015Peripheral opioid antagonist enhances the effect of anti-tumor drug by blocking a cell growth-suppressive pathway in vivo.11
258538622015Peripheral opioid antagonist enhances the effect of anti-tumor drug by blocking a cell growth-suppressive pathway in vivo.11
238569082013Targeting the opioid growth factor: opioid growth factor receptor axis for treatment of human ovarian cancer.16
238569082013Targeting the opioid growth factor: opioid growth factor receptor axis for treatment of human ovarian cancer.16
223285952012Under-expression of the opioid growth factor receptor promotes progression of human ovarian cancer.3
223285952012Under-expression of the opioid growth factor receptor promotes progression of human ovarian cancer.3
199233572010The opioid growth factor-opioid growth factor receptor axis regulates cell proliferation of human hepatocellular cancer.12
199233572010The opioid growth factor-opioid growth factor receptor axis regulates cell proliferation of human hepatocellular cancer.12
189231422009The OGF-OGFr axis utilizes the p16INK4a and p21WAF1/CIP1 pathways to restrict normal cell proliferation.40
192445452009Dependence on nuclear localization signals of the opioid growth factor receptor in the regulation of cell proliferation.8
192975472009Cell proliferation of human ovarian cancer is regulated by the opioid growth factor-opioid growth factor receptor axis.22

Citation

Dessen P

OGFR (opioid growth factor receptor)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43878