Identity
HGNC
LOCATION
17q21.32
LOCUSID
ALIAS
C53,HSF-27,IC53,LZAP,MST016,OK/SW-cl.114,PP1553
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80279
MIM: 608202
HGNC: 18673
Ensembl: ENSG00000108465
Variants:
dbSNP: 80279
ClinVar: 80279
TCGA: ENSG00000108465
COSMIC: CDK5RAP3
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38725860 | 2024 | TSPAN6 reinforces the malignant progression of glioblastoma via interacting with CDK5RAP3 and regulating STAT3 signaling pathway. | 1 |
| 38725860 | 2024 | TSPAN6 reinforces the malignant progression of glioblastoma via interacting with CDK5RAP3 and regulating STAT3 signaling pathway. | 1 |
| 35999359 | 2023 | CDK5RAP3 acts as a tumour suppressor in gastric cancer through the infiltration and polarization of tumour-associated macrophages. | 4 |
| 35999359 | 2023 | CDK5RAP3 acts as a tumour suppressor in gastric cancer through the infiltration and polarization of tumour-associated macrophages. | 4 |
| 35219640 | 2022 | CDK5RAP3 acts as a putative tumor inhibitor in papillary thyroid carcinoma via modulation of Akt/GSK-3β/Wnt/β-catenin signaling. | 1 |
| 35219640 | 2022 | CDK5RAP3 acts as a putative tumor inhibitor in papillary thyroid carcinoma via modulation of Akt/GSK-3β/Wnt/β-catenin signaling. | 1 |
| 32606358 | 2020 | CDK5RAP3 as tumour suppressor negatively regulates self-renewal and invasion and is regulated by ERK1/2 signalling in human gastric cancer. | 7 |
| 32606358 | 2020 | CDK5RAP3 as tumour suppressor negatively regulates self-renewal and invasion and is regulated by ERK1/2 signalling in human gastric cancer. | 7 |
| 30864700 | 2019 | Overexpression of IC53d promotes the proliferation of gastric cancer cells by activating the AKT/GSK3β/cyclin D1 signaling pathway. | 11 |
| 30954448 | 2019 | C53: A novel particulate guanylyl cyclase B receptor activator that has sustained activity in vivo with anti-fibrotic actions in human cardiac and renal fibroblasts. | 17 |
| 31061682 | 2019 | CDK5RAP3 Participates in Autophagy Regulation and Is Downregulated in Renal Cancer. | 5 |
| 30864700 | 2019 | Overexpression of IC53d promotes the proliferation of gastric cancer cells by activating the AKT/GSK3β/cyclin D1 signaling pathway. | 11 |
| 30954448 | 2019 | C53: A novel particulate guanylyl cyclase B receptor activator that has sustained activity in vivo with anti-fibrotic actions in human cardiac and renal fibroblasts. | 17 |
| 31061682 | 2019 | CDK5RAP3 Participates in Autophagy Regulation and Is Downregulated in Renal Cancer. | 5 |
| 29540196 | 2018 | CDK5RAP3 suppresses Wnt/β-catenin signaling by inhibiting AKT phosphorylation in gastric cancer. | 24 |
Citation
Dessen P
CDK5RAP3 (CDK5 regulatory subunit associated protein 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43880/cdk5rap3
