Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5644
MIM: 276000
HGNC: 9475
Ensembl: ENSG00000204983
Variants:
dbSNP: 5644
ClinVar: 5644
TCGA: ENSG00000204983
COSMIC: PRSS1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000204983 | ENST00000311737 | P07477 |
| ENSG00000204983 | ENST00000486171 | E7EQ64 |
| ENSG00000204983 | ENST00000492062 | H0Y8D1 |
| ENSG00000204983 | ENST00000619214 | A6XGL3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36191639 | 2023 | Pancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression. | 0 |
| 36883543 | 2023 | [Influence of environmental factors and polymorphic loci rs6580502 of the SPINK1 gene, rs10273639 of the PRSS1 gene, rs213950 of the CFTR gene on the risk of developing acute alcoholic-alimentary pancreatitis]. | 0 |
| 36191639 | 2023 | Pancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression. | 0 |
| 36883543 | 2023 | [Influence of environmental factors and polymorphic loci rs6580502 of the SPINK1 gene, rs10273639 of the PRSS1 gene, rs213950 of the CFTR gene on the risk of developing acute alcoholic-alimentary pancreatitis]. | 0 |
| 35089416 | 2022 | Trypsinogen (PRSS1 and PRSS2) gene dosage correlates with pancreatitis risk across genetic and transgenic studies: a systematic review and re-analysis. | 4 |
| 36369231 | 2022 | A rare PRSS1 p.S127C mutation is associated with chronic pancreatitis and causes misfolding-induced ER-stress. | 1 |
| 35089416 | 2022 | Trypsinogen (PRSS1 and PRSS2) gene dosage correlates with pancreatitis risk across genetic and transgenic studies: a systematic review and re-analysis. | 4 |
| 36369231 | 2022 | A rare PRSS1 p.S127C mutation is associated with chronic pancreatitis and causes misfolding-induced ER-stress. | 1 |
| 32669225 | 2021 | A high prevalence of genetic polymorphisms in idiopathic and alcohol-associated chronic pancreatitis patients in Ireland. | 3 |
| 33257277 | 2021 | Clinical interpretation of PRSS1 variants in patients with pancreatitis. | 2 |
| 33515547 | 2021 | Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis. | 13 |
| 33867821 | 2021 | Silencing PRSS1 suppresses the growth and proliferation of gastric carcinoma cells via the ERK pathway. | 4 |
| 32669225 | 2021 | A high prevalence of genetic polymorphisms in idiopathic and alcohol-associated chronic pancreatitis patients in Ireland. | 3 |
| 33257277 | 2021 | Clinical interpretation of PRSS1 variants in patients with pancreatitis. | 2 |
| 33515547 | 2021 | Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis. | 13 |
Citation
Dessen P
PRSS1 (serine protease 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43895/prss1
