Identity
HGNC
LOCATION
6p21.1
LOCUSID
ALIAS
PT-ALPHA,PTA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 171558
MIM: 606817
HGNC: 21290
Ensembl: ENSG00000171611
Variants:
dbSNP: 171558
ClinVar: 171558
TCGA: ENSG00000171611
COSMIC: PTCRA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171611 | ENST00000304672 | Q6ISU1 |
| ENSG00000171611 | ENST00000441198 | Q6ISU1 |
| ENSG00000171611 | ENST00000446507 | Q6ISU1 |
| ENSG00000171611 | ENST00000616441 | A0A087WTE9 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Notch signaling pathway | KEGG | ko04330 |
| Notch signaling pathway | KEGG | hsa04330 |
| Transcriptional misregulation in cancer | KEGG | ko05202 |
| Transcriptional misregulation in cancer | KEGG | hsa05202 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33652347 | 2021 | Generation of self-reactive, shared T-cell receptor α chains in the human thymus. | 4 |
| 33652347 | 2021 | Generation of self-reactive, shared T-cell receptor α chains in the human thymus. | 4 |
| 19019335 | 2009 | Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. | 33 |
| 19527514 | 2009 | Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants. | 34 |
| 19019335 | 2009 | Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. | 33 |
| 19527514 | 2009 | Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants. | 34 |
| 18818748 | 2008 | Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. | 37 |
| 18818748 | 2008 | Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. | 37 |
| 17823309 | 2007 | Identification of CMS as a cytosolic adaptor of the human pTalpha chain involved in pre-TCR function. | 4 |
| 17823309 | 2007 | Identification of CMS as a cytosolic adaptor of the human pTalpha chain involved in pre-TCR function. | 4 |
| 14500629 | 2003 | Extrathymic TCR gene rearrangement in human small intestine: identification of new splice forms of recombination activating gene-1 mRNA with selective tissue expression. | 8 |
| 14500629 | 2003 | Extrathymic TCR gene rearrangement in human small intestine: identification of new splice forms of recombination activating gene-1 mRNA with selective tissue expression. | 8 |
| 11891328 | 2002 | Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis. | 66 |
| 11891328 | 2002 | Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis. | 66 |
Citation
Dessen P
PTCRA (pre T cell antigen receptor alpha)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43929/ptcra
