JADE1 (jade family PHD finger 1)

2007-02-01  

Identity

HGNC
JADE1
LOCATION
4q28.2
LOCUSID
79960
ALIAS
PHF17
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79960
MIM: 610514
HGNC: 30027
Ensembl: ENSG00000077684

Variants:

dbSNP: 79960
ClinVar: 79960
TCGA: ENSG00000077684
COSMIC: JADE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000077684ENST00000226319Q6IE81
ENSG00000077684ENST00000413543Q6IE81
ENSG00000077684ENST00000452328Q6IE81
ENSG00000077684ENST00000503785D6RC05
ENSG00000077684ENST00000504089D6RFK0
ENSG00000077684ENST00000507833D6RBB3
ENSG00000077684ENST00000508997D6RCS1
ENSG00000077684ENST00000510308D6RGE7
ENSG00000077684ENST00000511647Q6IE81
ENSG00000077684ENST00000511925D6RAS5
ENSG00000077684ENST00000512960Q6IE81
ENSG00000077684ENST00000514740D6RE74
ENSG00000077684ENST00000610919Q6IE81
ENSG00000077684ENST00000611140Q6IE81

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
371755312023MicroRNA-155-5p Targets JADE-1, Promoting Proliferation, Migration, and Invasion in Clear Cell Renal Cell Carcinoma Cells.2
371755312023MicroRNA-155-5p Targets JADE-1, Promoting Proliferation, Migration, and Invasion in Clear Cell Renal Cell Carcinoma Cells.2
347197652022Genome-wide association study and functional validation implicates JADE1 in tauopathy.10
347197652022Genome-wide association study and functional validation implicates JADE1 in tauopathy.10
293827222018The scaffolding protein JADE1 physically links the acetyltransferase subunit HBO1 with its histone H3-H4 substrate.13
293827222018The scaffolding protein JADE1 physically links the acetyltransferase subunit HBO1 with its histone H3-H4 substrate.13
281347662017Plasma Triglyceride Levels May Be Modulated by Gene Expression of IQCJ, NXPH1, PHF17 and MYB in Humans.10
281347662017Plasma Triglyceride Levels May Be Modulated by Gene Expression of IQCJ, NXPH1, PHF17 and MYB in Humans.10
269195592016Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.6
271555212016Structure, function and regulation of jade family PHD finger 1 (JADE1).13
271604562016Novel Genetic Loci Associated with the Plasma Triglyceride Response to an Omega-3 Fatty Acid Supplementation.13
269195592016Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.6
271555212016Structure, function and regulation of jade family PHD finger 1 (JADE1).13
271604562016Novel Genetic Loci Associated with the Plasma Triglyceride Response to an Omega-3 Fatty Acid Supplementation.13
261512252015The novel function of JADE1S in cytokinesis of epithelial cells.7

Citation

Dessen P

JADE1 (jade family PHD finger 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43934/jade1-(jade-family-phd-finger-1)