Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1553
MIM: 608055
HGNC: 2608
Ensembl: ENSG00000197838
Variants:
dbSNP: 1553
ClinVar: 1553
TCGA: ENSG00000197838
COSMIC: CYP2A13
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000197838 | ENST00000330436 | Q16696 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA134521193 | coumarin | Chemical | VariantAnnotation | associated | PK | 29342418 | |
| PA166181759 | nnk | Chemical | VipGene | associated | |||
| PA445876 | Tobacco Use Disorder | Disease | ClinicalAnnotation | associated | PD | ||
| PA450626 | nicotine | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PK | PD | 29342418 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33703988 | 2021 | Molecular docking and oxidation kinetics of 3-phenyl coumarin derivatives by human CYP2A13. | 4 |
| 34830188 | 2021 | Genetic and Enzymatic Characteristics of CYP2A13 in Relation to Lung Damage. | 0 |
| 33703988 | 2021 | Molecular docking and oxidation kinetics of 3-phenyl coumarin derivatives by human CYP2A13. | 4 |
| 34830188 | 2021 | Genetic and Enzymatic Characteristics of CYP2A13 in Relation to Lung Damage. | 0 |
| 33327254 | 2020 | Association between CYP2A13 polymorphisms and lung cancer: A protocol for systematic review and meta-analysis. | 0 |
| 33327254 | 2020 | Association between CYP2A13 polymorphisms and lung cancer: A protocol for systematic review and meta-analysis. | 0 |
| 30807688 | 2019 | HapMap-based study: CYP2A13 may be a potential key metabolic enzyme gene in the carcinogenesis of lung cancer in non-smokers. | 3 |
| 30807688 | 2019 | HapMap-based study: CYP2A13 may be a potential key metabolic enzyme gene in the carcinogenesis of lung cancer in non-smokers. | 3 |
| 28648140 | 2018 | Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants. | 5 |
| 29652224 | 2018 | In vitro functional analysis of human cytochrome P450 2A13 genetic variants: P450 2A13*2, *3, *4, and *10. | 7 |
| 28648140 | 2018 | Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants. | 5 |
| 29652224 | 2018 | In vitro functional analysis of human cytochrome P450 2A13 genetic variants: P450 2A13*2, *3, *4, and *10. | 7 |
| 27567546 | 2016 | In vitro metabolism of N'-Nitrosonornicotine catalyzed by cytochrome P450 2A13 and its inhibition by nicotine, N'-Nitrosoanatabine and N'-Nitrosoanabasine. | 1 |
| 27725446 | 2016 | CYP2A13 Genetic Polymorphisms in Relation to the Risk of Bladder Cancer in Japanese Smokers. | 3 |
| 27567546 | 2016 | In vitro metabolism of N'-Nitrosonornicotine catalyzed by cytochrome P450 2A13 and its inhibition by nicotine, N'-Nitrosoanatabine and N'-Nitrosoanabasine. | 1 |
Citation
Dessen P
CYP2A13 (cytochrome P450 family 2 subfamily A member 13)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43982/cyp2a13
