Identity
HGNC
LOCATION
14q32.13
LOCUSID
ALIAS
PAI-3,PAI3,PCI,PCI-B,PLANH3,PROCI
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5104
MIM: 601841
HGNC: 8723
Ensembl: ENSG00000188488
Variants:
dbSNP: 5104
ClinVar: 5104
TCGA: ENSG00000188488
COSMIC: SERPINA5
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443622 | Carcinoma, Non-Small-Cell Lung | Disease | ClinicalAnnotation | associated | PD | 31616045 | |
| PA445846 | Thrombocytopenia | Disease | ClinicalAnnotation | associated | PD | 31616045 | |
| PA448803 | carboplatin | Chemical | ClinicalAnnotation | associated | PD | 31616045 | |
| PA449748 | gemcitabine | Chemical | ClinicalAnnotation | associated | PD | 31616045 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35717024 | 2023 | SERPINA5 may promote the development of preeclampsia by disruption of the uPA/uPAR pathway. | 1 |
| 37327267 | 2023 | The SERPINA5 coding variant E228Q does not contribute to clinicopathologic characteristics in Alzheimer's disease: A cross-sectional study. | 0 |
| 35717024 | 2023 | SERPINA5 may promote the development of preeclampsia by disruption of the uPA/uPAR pathway. | 1 |
| 37327267 | 2023 | The SERPINA5 coding variant E228Q does not contribute to clinicopathologic characteristics in Alzheimer's disease: A cross-sectional study. | 0 |
| 34964303 | 2022 | Proteomic analysis of human articular cartilage unravels the dyscoagulation in osteoarthritis and the potential value of serpinA5 as a biomarker for osteoarthritis. | 5 |
| 36000536 | 2022 | SERPINA5 promotes tumour cell proliferation by modulating the PI3K/AKT/mTOR signalling pathway in gastric cancer. | 7 |
| 36177795 | 2022 | ANXA2, SP17, SERPINA5, PRDX2 genes, and sperm DNA fragmentation differentially represented in male partners of infertile couples with normal and abnormal sperm parameters. | 3 |
| 34964303 | 2022 | Proteomic analysis of human articular cartilage unravels the dyscoagulation in osteoarthritis and the potential value of serpinA5 as a biomarker for osteoarthritis. | 5 |
| 36000536 | 2022 | SERPINA5 promotes tumour cell proliferation by modulating the PI3K/AKT/mTOR signalling pathway in gastric cancer. | 7 |
| 36177795 | 2022 | ANXA2, SP17, SERPINA5, PRDX2 genes, and sperm DNA fragmentation differentially represented in male partners of infertile couples with normal and abnormal sperm parameters. | 3 |
| 34009669 | 2021 | SERPIN A5 may have a potential as a biomarker in reflecting the improvement of semen quality in infertile men who underwent varicocele repair. | 2 |
| 34837923 | 2021 | Evaluation the Presence of SERPINA5 (Exon 3) and FTO rs9939609 Polymorphisms in Papillary Thyroid Cancer Patients. | 5 |
| 34009669 | 2021 | SERPIN A5 may have a potential as a biomarker in reflecting the improvement of semen quality in infertile men who underwent varicocele repair. | 2 |
| 34837923 | 2021 | Evaluation the Presence of SERPINA5 (Exon 3) and FTO rs9939609 Polymorphisms in Papillary Thyroid Cancer Patients. | 5 |
| 30715578 | 2020 | Genetic association in female stress urinary incontinence based on proteomic findings: a case-control study. | 1 |
Citation
Dessen P
SERPINA5 (serpin family A member 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43985/serpina5
