Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 90070
MIM: 607360
HGNC: 16430
Ensembl: ENSG00000135413
Variants:
dbSNP: 90070
ClinVar: 90070
TCGA: ENSG00000135413
COSMIC: LACRT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000135413 | ENST00000257867 | Q9GZZ8 |
| ENSG00000135413 | ENST00000546721 | H0YI00 |
| ENSG00000135413 | ENST00000547511 | F8W0V3 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33187980 | 2021 | Lacritin proteoforms prevent tear film collapse and maintain epithelial homeostasis. | 12 |
| 33187980 | 2021 | Lacritin proteoforms prevent tear film collapse and maintain epithelial homeostasis. | 12 |
| 32274735 | 2020 | The Lacritin-Syndecan-1-Heparanase Axis in Dry Eye Disease. | 2 |
| 32274735 | 2020 | The Lacritin-Syndecan-1-Heparanase Axis in Dry Eye Disease. | 2 |
| 28419103 | 2017 | Establishment of a tear protein biomarker panel differentiating between Graves' disease with or without orbitopathy. | 8 |
| 28419103 | 2017 | Establishment of a tear protein biomarker panel differentiating between Graves' disease with or without orbitopathy. | 8 |
| 26670139 | 2015 | Lacritin Salvages Human Corneal Epithelial Cells from Lipopolysaccharide Induced Cell Death. | 6 |
| 26670139 | 2015 | Lacritin Salvages Human Corneal Epithelial Cells from Lipopolysaccharide Induced Cell Death. | 6 |
| 24942736 | 2014 | A cleavage-potentiated fragment of tear lacritin is bactericidal. | 21 |
| 24942736 | 2014 | A cleavage-potentiated fragment of tear lacritin is bactericidal. | 21 |
| 23308132 | 2013 | Pathogen induced changes in the protein profile of human tears from Fusarium keratitis patients. | 31 |
| 23422824 | 2013 | Conserved regional 3' grouping of rare codons in the coding sequence of ocular prosecretory mitogen lacritin. | 5 |
| 23425695 | 2013 | Tissue transglutaminase is a negative regulator of monomeric lacritin bioactivity. | 16 |
| 23482462 | 2013 | Lacritin-induced secretion of tear proteins from cultured monkey lacrimal acinar cells. | 13 |
| 23504321 | 2013 | Targeting of heparanase-modified syndecan-1 by prosecretory mitogen lacritin requires conserved core GAGAL plus heparan and chondroitin sulfate as a novel hybrid binding site that enhances selectivity. | 23 |
Citation
Dessen P
LACRT (lacritin)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43987/lacrt
