SERBP1 (SERPINE1 mRNA binding protein 1)

2007-02-01  

Identity

HGNC
SERBP1
LOCATION
1p31.3
LOCUSID
26135
ALIAS
CGI-55,CHD3IP,HABP4L,PAI-RBP1,PAIRBP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 26135
MIM: 607378
HGNC: 17860
Ensembl: ENSG00000142864

Variants:

dbSNP: 26135
ClinVar: 26135
TCGA: ENSG00000142864
COSMIC: SERBP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000142864ENST00000361219Q8NC51
ENSG00000142864ENST00000370990Q8NC51
ENSG00000142864ENST00000370994Q8NC51
ENSG00000142864ENST00000370994Q5VU21
ENSG00000142864ENST00000370995Q8NC51

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
372400622023SERPINE1 mRNA Binding Protein 1 Is Associated with Ischemic Stroke Risk: A Comprehensive Molecular-Genetic and Bioinformatics Analysis of SERBP1 SNPs.0
372400622023SERPINE1 mRNA Binding Protein 1 Is Associated with Ischemic Stroke Risk: A Comprehensive Molecular-Genetic and Bioinformatics Analysis of SERBP1 SNPs.0
351565132022YY1-induced long non-coding RNA small nucleolar RNA host gene 8 promotes the tumorigenesis of melanoma via the microRNA-656-3p/SERPINE1 mRNA binding protein 1 axis.6
351565132022YY1-induced long non-coding RNA small nucleolar RNA host gene 8 promotes the tumorigenesis of melanoma via the microRNA-656-3p/SERPINE1 mRNA binding protein 1 axis.6
335260472021miR-362-3p acts as a tumor suppressor by targeting SERBP1 in ovarian cancer.9
338317872021CircRNA circBACH1 (hsa_circ_0061395) serves as a miR-656-3p sponge to facilitate hepatocellular carcinoma progression through increasing SERBP1 expression.8
342709022021G-Quadruplex-Induced Liquid-Liquid Phase Separation in Biomimetic Protocells.16
347845192021Circ_0046600 promotes hepatocellular carcinoma progression via up-regulating SERBP1 through sequestering miR-1258.3
348369412021A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division.5
335260472021miR-362-3p acts as a tumor suppressor by targeting SERBP1 in ovarian cancer.9
338317872021CircRNA circBACH1 (hsa_circ_0061395) serves as a miR-656-3p sponge to facilitate hepatocellular carcinoma progression through increasing SERBP1 expression.8
342709022021G-Quadruplex-Induced Liquid-Liquid Phase Separation in Biomimetic Protocells.16
347845192021Circ_0046600 promotes hepatocellular carcinoma progression via up-regulating SERBP1 through sequestering miR-1258.3
348369412021A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division.5
327627762020The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation.40

Citation

Dessen P

SERBP1 (SERPINE1 mRNA binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45522