Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3589
MIM: 147681
HGNC: 5966
Ensembl: ENSG00000095752
Variants:
dbSNP: 3589
ClinVar: 3589
TCGA: ENSG00000095752
COSMIC: IL11
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10074 | escitalopram | Chemical | ClinicalAnnotation | associated | PD | 23142150 | |
| PA447278 | Depression | Disease | ClinicalAnnotation | associated | PD | 23142150 | |
| PA449015 | citalopram | Chemical | MultilinkAnnotation | associated | 25916525 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38429845 | 2024 | Single-cell deconvolution algorithms analysis unveils autocrine IL11-mediated resistance to docetaxel in prostate cancer via activation of the JAK1/STAT4 pathway. | 0 |
| 38455057 | 2024 | IL11-mediated stromal cell activation may not be the master regulator of pro-fibrotic signaling downstream of TGFβ. | 0 |
| 38643817 | 2024 | Serum levels of IL-9 and IL-11 serve as predictors for the occurrence of early neurologic deterioration in patients with cerebral infarction. | 0 |
| 38679415 | 2024 | Targeting IL-11 to reduce fibrocyte circulation and lung accumulation in animal models of pulmonary hypertension-associated lung fibrosis. | 0 |
| 38429845 | 2024 | Single-cell deconvolution algorithms analysis unveils autocrine IL11-mediated resistance to docetaxel in prostate cancer via activation of the JAK1/STAT4 pathway. | 0 |
| 38455057 | 2024 | IL11-mediated stromal cell activation may not be the master regulator of pro-fibrotic signaling downstream of TGFβ. | 0 |
| 38643817 | 2024 | Serum levels of IL-9 and IL-11 serve as predictors for the occurrence of early neurologic deterioration in patients with cerebral infarction. | 0 |
| 38679415 | 2024 | Targeting IL-11 to reduce fibrocyte circulation and lung accumulation in animal models of pulmonary hypertension-associated lung fibrosis. | 0 |
| 36521373 | 2023 | Anti-apoptosis effect of recombinant human interleukin-11 in neonatal hypoxic-ischemic rats through activating the IL-11Rα/STAT3 signaling pathway. | 1 |
| 36758859 | 2023 | IL-11 drives the phenotypic transformation of tracheal epithelial cells and fibroblasts to enhance abnormal repair after tracheal injury. | 3 |
| 36834778 | 2023 | The Interleukin-11/IL-11 Receptor Promotes Glioblastoma Survival and Invasion under Glucose-Starved Conditions through Enhanced Glutaminolysis. | 2 |
| 36976735 | 2023 | [Interleukin-11 in Pathologies of the Nervous System]. | 1 |
| 37153732 | 2023 | IL11 signaling mediates piR-2158 suppression of cell stemness and angiogenesis in breast cancer. | 6 |
| 37291792 | 2023 | Elevated interleukin-11 in systemic sclerosis and role in disease pathogenesis. | 4 |
| 37401665 | 2023 | Blockade of IL-11 Trans-Signaling or JAK2/STAT3 Signaling Ameliorates the Profibrotic Effect of IL-11. | 2 |
Citation
Dessen P
IL11 (interleukin 11)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45534/il11
