Identity
HGNC
LOCATION
Xq23
LOCUSID
ALIAS
ACS4,FACL4,LACS4,MRX63,MRX68
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2182
MIM: 300157
HGNC: 3571
Ensembl: ENSG00000068366
Variants:
dbSNP: 2182
ClinVar: 2182
TCGA: ENSG00000068366
COSMIC: ACSL4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38040804 | 2024 | RBM45 reprograms lipid metabolism promoting hepatocellular carcinoma via Rictor and ACSL1/ACSL4. | 1 |
| 38073444 | 2024 | Methylation Regulation of LPCAT3 Improves Osteoarthritis by Regulating ACSL4 to Inhibit Chondrocyte Ferroptosis. | 1 |
| 38088220 | 2024 | Loss of nephric augmenter of liver regeneration facilitates acute kidney injury via ACSL4-mediated ferroptosis. | 2 |
| 38186303 | 2024 | SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1. | 4 |
| 38215103 | 2024 | Serum ACSL4 levels in patients with ST-segment elevation myocardial infarction (STEMI) and its association with one-year major adverse cardiovascular events (MACE): A prospective cohort study. | 0 |
| 38367927 | 2024 | The ERK-cPLA2-ACSL4 axis mediating M2 macrophages ferroptosis impedes mucosal healing in ulcerative colitis. | 1 |
| 38462207 | 2024 | METTL3 promotes trophoblast ferroptosis in preeclampsia by stabilizing the ACSL4 m(6)A modification. | 0 |
| 38466744 | 2024 | Autocrine phosphatase PDP2 inhibits ferroptosis by dephosphorylating ACSL4 in the Luminal A Breast Cancer. | 0 |
| 38615921 | 2024 | ACSL4 promotes malignant progression of Hepatocellular carcinoma by targeting PAK2 transcription. | 0 |
| 38710444 | 2024 | Long-chain acyl-CoA synthetase-4 regulates endometrial decidualization through a fatty acid β-oxidation pathway rather than lipid droplet accumulation. | 0 |
| 38842200 | 2024 | SIAH2-Mediated Degradation of ACSL4 Inhibits the Anti-Tumor Activity of CD8+ T Cells in Hepatocellular Carcinoma. | 0 |
| 38040804 | 2024 | RBM45 reprograms lipid metabolism promoting hepatocellular carcinoma via Rictor and ACSL1/ACSL4. | 1 |
| 38073444 | 2024 | Methylation Regulation of LPCAT3 Improves Osteoarthritis by Regulating ACSL4 to Inhibit Chondrocyte Ferroptosis. | 1 |
| 38088220 | 2024 | Loss of nephric augmenter of liver regeneration facilitates acute kidney injury via ACSL4-mediated ferroptosis. | 2 |
| 38186303 | 2024 | SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1. | 4 |
Citation
Dessen P
ACSL4 (acyl-CoA synthetase long chain family member 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45548/acsl4
