TCF21 (transcription factor 21)

2007-02-01  

Identity

HGNC
TCF21
LOCATION
6q23.2
LOCUSID
6943
ALIAS
POD1,bHLHa23

Other Information

Locus ID:

NCBI: 6943
MIM: 603306
HGNC: 11632
Ensembl: ENSG00000118526

Variants:

dbSNP: 6943
ClinVar: 6943
TCGA: ENSG00000118526
COSMIC: TCF21

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118526ENST00000237316O43680
ENSG00000118526ENST00000367882O43680

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382506102024Transcription factor 21 rs12190287 polymorphism is related to stable angina and ST elevation myocardial infarction in a Chinese Population.0
382506102024Transcription factor 21 rs12190287 polymorphism is related to stable angina and ST elevation myocardial infarction in a Chinese Population.0
369976642023Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs.5
373910232023Transcription factor 21 gene and prognosis in a coronary population.1
381973162023TCF21 rs2327429 and TCF21 rs12190287 are associated with colorectal cancer in a Chinese population.0
369976642023Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs.5
373910232023Transcription factor 21 gene and prognosis in a coronary population.1
381973162023TCF21 rs2327429 and TCF21 rs12190287 are associated with colorectal cancer in a Chinese population.0
351485832022Relationships among Immune Score, TCF21 Methylation, Risk-factor Level, and Prognosis in Prostate Cancer.0
356039522022N-type calcium channel v2.2 is a target of TCF21 in adrenocortical carcinomas.1
351485832022Relationships among Immune Score, TCF21 Methylation, Risk-factor Level, and Prognosis in Prostate Cancer.0
356039522022N-type calcium channel v2.2 is a target of TCF21 in adrenocortical carcinomas.1
336935402021Increased SUMOylation of TCF21 improves its stability and function in human endometriotic stromal cells†.0
341483072021Studies on the Role of the Transcription Factor Tcf21 in the Transdifferentiation of Parietal Epithelial Cells into Podocyte-Like Cells.1
343232852021Immunohistological score of transcription factor 21 had a positive correlation with its urinary excretion and proteinuria in immunoglobulin A nephropathy.2

Citation

Dessen P

TCF21 (transcription factor 21)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45561/cancer-prone-explorer/favicon/js/lib/popper.js