Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5028
MIM: 601167
HGNC: 8539
Ensembl: ENSG00000169860
Variants:
dbSNP: 5028
ClinVar: 5028
TCGA: ENSG00000169860
COSMIC: P2RY1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000169860 | ENST00000305097 | P47900 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA166156291 | rs701265 | Variant | VipGene | associated | 16581111, 15514209 | ||
| PA166156310 | rs1065776 | Variant | VipGene | associated | 17559347, 15757620 | ||
| PA174 | GNAQ | Gene | Pathway | associated | 20938371 | ||
| PA176 | GNB3 | Gene | Pathway | associated | 20938371 | ||
| PA28764 | GNA11 | Gene | Pathway | associated | 20938371 | ||
| PA28765 | GNA12 | Gene | Pathway | associated | 20938371 | ||
| PA28766 | GNA13 | Gene | Pathway | associated | 20938371 | ||
| PA28768 | GNA15 | Gene | Pathway | associated | 20938371 | ||
| PA445019 | Myocardial Infarction | Disease | ClinicalAnnotation | associated | PD | 15757620, 17559347, 22940005 | |
| PA448497 | aspirin | Chemical | ClinicalAnnotation | associated | PD | 15757620, 17559347, 22940005 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37442808 | 2024 | Exploring bias in platelet P2Y(1) signalling: Host defence versus haemostasis. | 2 |
| 38159881 | 2024 | Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics. | 0 |
| 37442808 | 2024 | Exploring bias in platelet P2Y(1) signalling: Host defence versus haemostasis. | 2 |
| 38159881 | 2024 | Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics. | 0 |
| 36681816 | 2023 | Association between P2Y1 and P2Y12 polymorphisms and acute myocardial infarction and ADP-induced platelet aggregation. | 0 |
| 36681816 | 2023 | Association between P2Y1 and P2Y12 polymorphisms and acute myocardial infarction and ADP-induced platelet aggregation. | 0 |
| 33435130 | 2021 | Nucleotides-Induced Changes in the Mechanical Properties of Living Endothelial Cells and Astrocytes, Analyzed by Atomic Force Microscopy. | 3 |
| 33435130 | 2021 | Nucleotides-Induced Changes in the Mechanical Properties of Living Endothelial Cells and Astrocytes, Analyzed by Atomic Force Microscopy. | 3 |
| 32159362 | 2020 | Purinergic signaling, DAMPs, and inflammation. | 91 |
| 32756482 | 2020 | Contribution of P2X4 Receptors to CNS Function and Pathophysiology. | 31 |
| 32159362 | 2020 | Purinergic signaling, DAMPs, and inflammation. | 91 |
| 32756482 | 2020 | Contribution of P2X4 Receptors to CNS Function and Pathophysiology. | 31 |
| 30914039 | 2019 | The TXA2R rs1131882, P2Y1 rs1371097 and GPIIIa rs2317676 three-loci interactions may increase the risk of carotid stenosis in patients with ischemic stroke. | 4 |
| 30919205 | 2019 | Autocrine stimulation of P2Y1 receptors is part of the purinergic signaling mechanism that regulates T cell activation. | 8 |
| 30914039 | 2019 | The TXA2R rs1131882, P2Y1 rs1371097 and GPIIIa rs2317676 three-loci interactions may increase the risk of carotid stenosis in patients with ischemic stroke. | 4 |
Citation
Dessen P
P2RY1 (purinergic receptor P2Y1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45562/p2ry1
