Identity
HGNC
LOCATION
1q41
LOCUSID
ALIAS
CANP2,CANPL2,CANPml,mCANP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 824
MIM: 114230
HGNC: 1479
Ensembl: ENSG00000162909
Variants:
dbSNP: 824
ClinVar: 824
TCGA: ENSG00000162909
COSMIC: CAPN2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000162909 | ENST00000295006 | P17655 |
| ENSG00000162909 | ENST00000433674 | P17655 |
| ENSG00000162909 | ENST00000434648 | C9JWY7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37663545 | 2023 | Rare variants in CAPN2 increase risk for isolated hypoplastic left heart syndrome. | 0 |
| 37663545 | 2023 | Rare variants in CAPN2 increase risk for isolated hypoplastic left heart syndrome. | 0 |
| 34191270 | 2021 | Variants in Genes of Calpain System as Modifiers of Spinocerebellar Ataxia Type 3 Phenotype. | 2 |
| 34381117 | 2021 | Cleavage and activation of LIM kinase 1 as a novel mechanism for calpain 2-mediated regulation of nuclear dynamics. | 4 |
| 34191270 | 2021 | Variants in Genes of Calpain System as Modifiers of Spinocerebellar Ataxia Type 3 Phenotype. | 2 |
| 34381117 | 2021 | Cleavage and activation of LIM kinase 1 as a novel mechanism for calpain 2-mediated regulation of nuclear dynamics. | 4 |
| 31680308 | 2020 | CAPN2 acts as an indicator of hepatitis B virus to induce hepatic fibrosis. | 4 |
| 33078830 | 2020 | Calpain-2 participates in the process of calpain-1 inactivation. | 8 |
| 31680308 | 2020 | CAPN2 acts as an indicator of hepatitis B virus to induce hepatic fibrosis. | 4 |
| 33078830 | 2020 | Calpain-2 participates in the process of calpain-1 inactivation. | 8 |
| 30417356 | 2019 | Calpain-2 protects against heat stress-induced cardiomyocyte apoptosis and heart dysfunction by blocking p38 mitogen-activated protein kinase activation. | 14 |
| 30448882 | 2019 | Calpain system protein expression and activity in ovarian cancer. | 16 |
| 31634637 | 2019 | Regulation of calpain 2 expression by miR-223 and miR-145. | 6 |
| 30417356 | 2019 | Calpain-2 protects against heat stress-induced cardiomyocyte apoptosis and heart dysfunction by blocking p38 mitogen-activated protein kinase activation. | 14 |
| 30448882 | 2019 | Calpain system protein expression and activity in ovarian cancer. | 16 |
Citation
Dessen P
CAPN2 (calpain 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45566/capn2
