Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6496
MIM: 603714
HGNC: 10889
Ensembl: ENSG00000138083
Variants:
dbSNP: 6496
ClinVar: 6496
TCGA: ENSG00000138083
COSMIC: SIX3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000138083 | ENST00000260653 | O95343 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35951005 | 2023 | Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man. | 2 |
| 35951005 | 2023 | Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man. | 2 |
| 34021861 | 2021 | miR-4306 Suppresses Proliferation of Esophageal Squamous Cell Carcinoma Cell by Targeting SIX3. | 3 |
| 34021861 | 2021 | miR-4306 Suppresses Proliferation of Esophageal Squamous Cell Carcinoma Cell by Targeting SIX3. | 3 |
| 32051553 | 2020 | The EGFR-ZNF263 signaling axis silences SIX3 in glioblastoma epigenetically. | 13 |
| 33264103 | 2020 | TRIM27 acts as an oncogene and regulates cell proliferation and metastasis in non-small cell lung cancer through SIX3-β-catenin signaling. | 17 |
| 32051553 | 2020 | The EGFR-ZNF263 signaling axis silences SIX3 in glioblastoma epigenetically. | 13 |
| 33264103 | 2020 | TRIM27 acts as an oncogene and regulates cell proliferation and metastasis in non-small cell lung cancer through SIX3-β-catenin signaling. | 17 |
| 30672777 | 2019 | Upregulation of sine oculis homeobox homolog 3 is associated with proliferation, invasion, migration, as well as poor prognosis of esophageal cancer. | 0 |
| 30672777 | 2019 | Upregulation of sine oculis homeobox homolog 3 is associated with proliferation, invasion, migration, as well as poor prognosis of esophageal cancer. | 0 |
| 28670735 | 2018 | SIX3 deletions and incomplete penetrance in families affected by holoprosencephaly. | 7 |
| 29463994 | 2018 | The Homeotic Protein SIX3 Suppresses Carcinogenesis and Metastasis through Recruiting the LSD1/NuRD(MTA3) Complex. | 18 |
| 30242153 | 2018 | Discovering human diabetes-risk gene function with genetics and physiological assays. | 33 |
| 28670735 | 2018 | SIX3 deletions and incomplete penetrance in families affected by holoprosencephaly. | 7 |
| 29463994 | 2018 | The Homeotic Protein SIX3 Suppresses Carcinogenesis and Metastasis through Recruiting the LSD1/NuRD(MTA3) Complex. | 18 |
Citation
Dessen P
SIX3 (SIX homeobox 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45571/six3
