ALB (albumin)

2007-02-01  

Identity

HGNC
ALB
LOCATION
4q13.3
LOCUSID
213
ALIAS
FDAHT,HSA,PRO0883,PRO0903,PRO1341
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 213
MIM: 103600
HGNC: 399
Ensembl: ENSG00000163631

Variants:

dbSNP: 213
ClinVar: 213
TCGA: ENSG00000163631
COSMIC: ALB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163631ENST00000295897P02768
ENSG00000163631ENST00000401494B7WNR0
ENSG00000163631ENST00000415165C9JKR2
ENSG00000163631ENST00000441319H7C013
ENSG00000163631ENST00000476441D6RCE7
ENSG00000163631ENST00000503124D6RHD5
ENSG00000163631ENST00000509063A0A0C4DGB6
ENSG00000163631ENST00000511370H0YA55
ENSG00000163631ENST00000621085P02768
ENSG00000163631ENST00000621628A0A087WWT3

Expression (GTEx)

0
5000
10000
15000
20000
25000
30000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Thyroid hormone synthesisKEGGhsa04918
Thyroid hormone synthesisKEGGko04918
DiseaseREACTOMER-HSA-1643685
Disorders of transmembrane transportersREACTOMER-HSA-5619115
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Response to elevated platelet cytosolic Ca2+REACTOMER-HSA-76005
Platelet degranulationREACTOMER-HSA-114608
Vesicle-mediated transportREACTOMER-HSA-5653656
Binding and Uptake of Ligands by Scavenger ReceptorsREACTOMER-HSA-2173782
Scavenging of heme from plasmaREACTOMER-HSA-2168880
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of vitamins, nucleosides, and related moleculesREACTOMER-HSA-425397
Transport of organic anionsREACTOMER-HSA-879518
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Lipid digestion, mobilization, and transportREACTOMER-HSA-73923
Lipoprotein metabolismREACTOMER-HSA-174824
HDL-mediated lipid transportREACTOMER-HSA-194223
Bile acid and bile salt metabolismREACTOMER-HSA-194068
Recycling of bile acids and saltsREACTOMER-HSA-159418
SLC transporter disordersREACTOMER-HSA-5619102
Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR)REACTOMER-HSA-5619110
Defective SLCO1B3 causes hyperbilirubinemia, Rotor type (HBLRR)REACTOMER-HSA-5619058

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381346422024Serum albumin mediates the associations between heavy metals and two novel systemic inflammation indexes among U.S. adults.3
383531272024Albumin influences leucocyte FcRn expression in the early days of kidney transplantation.0
387363682024Familial dysalbuminemic hyperthyroxinemia (FDH) due to Arg242 His variant in ALB gene in Turkish children.0
381346422024Serum albumin mediates the associations between heavy metals and two novel systemic inflammation indexes among U.S. adults.3
383531272024Albumin influences leucocyte FcRn expression in the early days of kidney transplantation.0
387363682024Familial dysalbuminemic hyperthyroxinemia (FDH) due to Arg242 His variant in ALB gene in Turkish children.0
347475212023Novel insights about albumin in cardiovascular diseases: Focus on heart failure.13
368409002023Changes in urinary albumin as a surrogate for kidney disease progression in people with type 2 diabetes.1
368781972023Serum Inflammation Parameters and Survival in Hepatocellular Carcinoma Patients: Importance of Albumin and Gamma-Glutamyltranspeptidase.2
369144832023Comment on Nagayama et al.: Low serum albumin concentration is associated with increased risk of osteoporosis in postmenopausal patients with rheumatoid arthritis.0
370553722023The effect of serum uric acid, bilirubin, and albumin levels on antioxidant status in HIV-negative immunocompetent cryptococcal meningitis patients with post-infectious inflammatory response syndrome.0
372296452023Lymphocytes, Mean Platelet Volume, and Albumin in Critically Ill COVID-19 Patients with Venous Thromboembolism.2
374549152023Determination of binding characteristics as a measure for effective albumin using different methods.1
374623052023[The Role of Blood Urea Nitrogen and C-Reactive Protein and Their Ratios to Albumin in Predicting Mortality in Crimean-Congo Hemorrhagic Fever].1
379267352023Highly oxidized albumin is cleared by liver sinusoidal endothelial cells via the receptors stabilin-1 and -2.1

Citation

Dessen P

ALB (albumin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45575