CD1C (CD1c molecule)

2007-02-01  

Identity

HGNC
CD1C
LOCATION
1q23.1
LOCUSID
911
ALIAS
BDCA1,CD1,CD1A,R7
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 911
MIM: 188340
HGNC: 1636
Ensembl: ENSG00000158481

Variants:

dbSNP: 911
ClinVar: 911
TCGA: ENSG00000158481
COSMIC: CD1C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158481ENST00000368170P29017
ENSG00000158481ENST00000443761H0Y6Y6

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Tight junctionKEGGko04530
Hematopoietic cell lineageKEGGko04640
Tight junctionKEGGhsa04530
Hematopoietic cell lineageKEGGhsa04640
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

References

Pubmed IDYearTitleCitations
367552592023CD1C is associated with breast cancer prognosis and immune infiltrates.4
380993112023Identifying CD1c as a potential biomarker by the comprehensive exploration of tumor mutational burden and immune infiltration in diffuse large B cell lymphoma.0
367552592023CD1C is associated with breast cancer prognosis and immune infiltrates.4
380993112023Identifying CD1c as a potential biomarker by the comprehensive exploration of tumor mutational burden and immune infiltration in diffuse large B cell lymphoma.0
333841572021Animal models for human group 1 CD1 protein function.8
345364212021Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells.2
333841572021Animal models for human group 1 CD1 protein function.8
345364212021Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells.2
297181932019Transcriptional Profiling of Age-Associated Gene Expression Changes in Human Circulatory CD1c+ Myeloid Dendritic Cell Subset.17
297181932019Transcriptional Profiling of Age-Associated Gene Expression Changes in Human Circulatory CD1c+ Myeloid Dendritic Cell Subset.17
277016682017CD1c+ Blood Dendritic Cells in Atopic Dermatitis are Premature and Can Produce Disease-specific Chemokines.3
283318532017Melanomas and Dysplastic Nevi Differ in Epidermal CD1c+ Dendritic Cell Count.5
277016682017CD1c+ Blood Dendritic Cells in Atopic Dermatitis are Premature and Can Produce Disease-specific Chemokines.3
283318532017Melanomas and Dysplastic Nevi Differ in Epidermal CD1c+ Dendritic Cell Count.5
268842072016Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells.35

Citation

Dessen P

CD1C (CD1c molecule)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45607