Identity
HGNC
LOCATION
1q25.3
LOCUSID
ALIAS
BAP-1,BAP1,DING,HIPI3,RING1B,RING2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6045
MIM: 608985
HGNC: 10061
Ensembl: ENSG00000121481
Variants:
dbSNP: 6045
ClinVar: 6045
TCGA: ENSG00000121481
COSMIC: RNF2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000121481 | ENST00000367509 | Q99496 |
| ENSG00000121481 | ENST00000367510 | Q99496 |
| ENSG00000121481 | ENST00000453650 | X6RFN3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36271315 | 2023 | The ubiquitin ligase RNF2 stabilizes ERα and modulates breast cancer progression. | 0 |
| 36932026 | 2023 | N-Terminally arginylated ubiquitin is attached to histone H2A by RING1B E3 ligase in human cells. | 0 |
| 37037816 | 2023 | RNF2 inhibits E-Cadherin transcription to promote hepatocellular carcinoma metastasis via inducing histone mono-ubiquitination. | 3 |
| 37806249 | 2023 | M phase-specific interaction between SBDS and RNF2 at the mitotic spindles regulates mitotic progression. | 0 |
| 36271315 | 2023 | The ubiquitin ligase RNF2 stabilizes ERα and modulates breast cancer progression. | 0 |
| 36932026 | 2023 | N-Terminally arginylated ubiquitin is attached to histone H2A by RING1B E3 ligase in human cells. | 0 |
| 37037816 | 2023 | RNF2 inhibits E-Cadherin transcription to promote hepatocellular carcinoma metastasis via inducing histone mono-ubiquitination. | 3 |
| 37806249 | 2023 | M phase-specific interaction between SBDS and RNF2 at the mitotic spindles regulates mitotic progression. | 0 |
| 33087530 | 2022 | Hospital-acquired serum phosphate derangements and their associated in-hospital mortality. | 4 |
| 34670117 | 2022 | RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4. | 5 |
| 35129056 | 2022 | DNA methyltransferase 3 beta regulates promoter methylation of microRNA-149 to augment esophageal squamous cell carcinoma development through the ring finger protein 2/Wnt/β-catenin axis. | 7 |
| 35158210 | 2022 | SBDS interacts with RNF2 and is degraded through RNF2-dependent ubiquitination. | 0 |
| 36198346 | 2022 | SPI1 mediates transcriptional activation of TPX2 and RNF2 to regulate the radiosensitivity of lung squamous cell carcinoma. | 1 |
| 33087530 | 2022 | Hospital-acquired serum phosphate derangements and their associated in-hospital mortality. | 4 |
| 34670117 | 2022 | RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4. | 5 |
Citation
Dessen P
RNF2 (ring finger protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45636/rnf2
