NUAK2 (NUAK family kinase 2)

2007-02-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
SNARK
FUSION GENES

Other Information

Locus ID:

NCBI: 81788
MIM: 608131
HGNC: 29558
Ensembl: ENSG00000163545

Variants:

dbSNP: 81788
ClinVar: 81788
TCGA: ENSG00000163545
COSMIC: NUAK2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163545ENST00000367157Q9H093

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
374297902024OTUD7B deubiquitinates and stabilizes YAP1 to upregulate NUAK2 expression, thus accelerating gastric cancer procession.2
374297902024OTUD7B deubiquitinates and stabilizes YAP1 to upregulate NUAK2 expression, thus accelerating gastric cancer procession.2
373574102023Circ_0000033 up-regulates NUAK2 by sequestering miR-378a-3p to promote breast tumorigenesis.1
374219422023Enhanced SARS-CoV-2 entry via UPR-dependent AMPK-related kinase NUAK2.8
373574102023Circ_0000033 up-regulates NUAK2 by sequestering miR-378a-3p to promote breast tumorigenesis.1
374219422023Enhanced SARS-CoV-2 entry via UPR-dependent AMPK-related kinase NUAK2.8
353430792022GPR65 promotes intestinal mucosal Th1 and Th17 cell differentiation and gut inflammation through downregulating NUAK2.13
353430792022GPR65 promotes intestinal mucosal Th1 and Th17 cell differentiation and gut inflammation through downregulating NUAK2.13
338805932021lncRNA FGD5‑AS1 promotes breast cancer progression by regulating the hsa‑miR‑195‑5p/NUAK2 axis.10
345586362021NUAK2 silencing inhibits the proliferation, migration and epithelial‑to‑mesenchymal transition of cervical cancer cells via upregulating CYFIP2.3
338805932021lncRNA FGD5‑AS1 promotes breast cancer progression by regulating the hsa‑miR‑195‑5p/NUAK2 axis.10
345586362021NUAK2 silencing inhibits the proliferation, migration and epithelial‑to‑mesenchymal transition of cervical cancer cells via upregulating CYFIP2.3
320011152020NUAK2 localization in normal skin and its expression in a variety of skin tumors with YAP.4
328459582020A loss-of-function NUAK2 mutation in humans causes anencephaly due to impaired Hippo-YAP signaling.19
320011152020NUAK2 localization in normal skin and its expression in a variety of skin tumors with YAP.4

Citation

Dessen P

NUAK2 (NUAK family kinase 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45666/nuak2