HP (haptoglobin)

2007-02-01  

Identity

HGNC
HP
LOCATION
16q22.2
LOCUSID
3240
ALIAS
BP,HP2ALPHA2,HPA1S
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3240
MIM: 140100
HGNC: 5141
Ensembl: ENSG00000257017

Variants:

dbSNP: 3240
ClinVar: 3240
TCGA: ENSG00000257017
COSMIC: HP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000257017ENST00000228226A0A087WU08
ENSG00000257017ENST00000355906P00738
ENSG00000257017ENST00000357763H0Y300
ENSG00000257017ENST00000398131P00738
ENSG00000257017ENST00000562526H3BMJ7
ENSG00000257017ENST00000564499H3BS21
ENSG00000257017ENST00000565574A0A0C4DGL8
ENSG00000257017ENST00000567185J3QR68
ENSG00000257017ENST00000567612J3QLC9
ENSG00000257017ENST00000568417J3KSV1
ENSG00000257017ENST00000569639J3QQI8
ENSG00000257017ENST00000570083P00738
ENSG00000257017ENST00000576168J3KRH2
ENSG00000257017ENST00000613898A0A087WU08

Expression (GTEx)

0
5000
10000
15000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Vesicle-mediated transportREACTOMER-HSA-5653656
Binding and Uptake of Ligands by Scavenger ReceptorsREACTOMER-HSA-2173782
Scavenging of heme from plasmaREACTOMER-HSA-2168880
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
359941082024Prediction of gestational diabetes mellitus and perinatal outcomes by plasma zonulin levels.1
379707252024Haptoglobin gene polymorphism and iron profile in sickle cell disease patients with inflammation in Yaounde, Cameroon.1
382199782024Differential expression of haptoglobin in individuals at clinical high risk of psychosis and its association with global functioning and clinical symptoms.0
384021722024Zonulin and copeptin relation to some metabolic markers in school-aged obese children.0
359941082024Prediction of gestational diabetes mellitus and perinatal outcomes by plasma zonulin levels.1
379707252024Haptoglobin gene polymorphism and iron profile in sickle cell disease patients with inflammation in Yaounde, Cameroon.1
382199782024Differential expression of haptoglobin in individuals at clinical high risk of psychosis and its association with global functioning and clinical symptoms.0
384021722024Zonulin and copeptin relation to some metabolic markers in school-aged obese children.0
359741122023Polymorphisms of haptoglobin modify the relationship between dietary iron and the risk of gestational iron-deficiency anemia.1
369633402023Correlates of Zonulin and Claudin-5, markers of intestinal and brain endothelial permeability, in Parkinson's Disease: A pilot study.0
370516692023A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease.1
371966002023Serum Zonulin Levels in Pediatric Migraine.0
372859512023Disease-Specific haptoglobin N-Glycosylation in inflammatory disorders between cancers and benign diseases of 3 types of female internal genital organs.1
374814762023Assessment of selected muscle damage markers and zonulin concentration after maximum-intensity exercise in men with type 1 diabetes treated with a personal insulin pump.0
375229482023Role of haptoglobin 2-2 genotype on disease progression and mortality among South Indian chronic kidney disease patients.0

Citation

Dessen P

HP (haptoglobin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45677