DACH2 (dachshund family transcription factor 2)

2007-02-01 Affiliation

Identity

HGNC

DACH2

LOCATION

Xq21.2

LOCUSID

117154

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 117154
MIM: 300608
HGNC: 16814
Ensembl: ENSG00000126733

Variants:

dbSNP: 117154
ClinVar: 117154
TCGA: ENSG00000126733
COSMIC: DACH2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000126733	ENST00000373125	Q96NX9
ENSG00000126733	ENST00000373131	Q96NX9
ENSG00000126733	ENST00000461604	D6RFG7
ENSG00000126733	ENST00000484479	H0Y912
ENSG00000126733	ENST00000506327	D6REJ4
ENSG00000126733	ENST00000508860	Q96NX9
ENSG00000126733	ENST00000510272	Q96NX9
ENSG00000126733	ENST00000613770	A0A087WTT5

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
25744029	2015	Prospective validation of DACH2 as a novel biomarker for prediction of metastasis and prognosis in muscle-invasive urothelial carcinoma of the bladder.	3
25744029	2015	Prospective validation of DACH2 as a novel biomarker for prediction of metastasis and prognosis in muscle-invasive urothelial carcinoma of the bladder.	3
25234129	2014	Exome sequencing identifies mutations in ABCD1 and DACH2 in two brothers with a distinct phenotype.	6
25234129	2014	Exome sequencing identifies mutations in ABCD1 and DACH2 in two brothers with a distinct phenotype.	6
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	15
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	15
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	105
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	105
15459172	2004	Mutation analysis of two candidate genes for premature ovarian failure, DACH2 and POF1B.	32
15459172	2004	Mutation analysis of two candidate genes for premature ovarian failure, DACH2 and POF1B.	32
12438735	2002	Most X;autosome translocations associated with premature ovarian failure do not interrupt X-linked genes.	13
12438735	2002	Most X;autosome translocations associated with premature ovarian failure do not interrupt X-linked genes.	13

Citation

Dessen P

DACH2 (dachshund family transcription factor 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45686/teaching-explorer/haematological-explorer/js/lib/meetings/