GH2 (growth hormone 2)

2007-02-01  

Identity

HGNC
LOCATION
17q23.3
LOCUSID
ALIAS
GH-V,GHB2,GHL,GHV,hGH-V
FUSION GENES

Other Information

Locus ID:

NCBI: 2689
MIM: 139240
HGNC: 4262
Ensembl: ENSG00000136487

Variants:

dbSNP: 2689
ClinVar: 2689
TCGA: ENSG00000136487
COSMIC: GH2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136487ENST00000332800P01242
ENSG00000136487ENST00000423893P01242
ENSG00000136487ENST00000423893A0A0M6L0J9
ENSG00000136487ENST00000449787P01242
ENSG00000136487ENST00000456543P01242
ENSG00000136487ENST00000622506A0A087WXJ5

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Neuroactive ligand-receptor interactionKEGGko04080
Jak-STAT signaling pathwayKEGGko04630
Cytokine-cytokine receptor interactionKEGGhsa04060
Neuroactive ligand-receptor interactionKEGGhsa04080
Jak-STAT signaling pathwayKEGGhsa04630
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Growth hormone receptor signalingREACTOMER-HSA-982772
Prolactin receptor signalingREACTOMER-HSA-1170546

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
265895702015Lower levels of placental growth hormone in early pregnancy in women with type 1 diabetes and large for gestational age infants.4
265895702015Lower levels of placental growth hormone in early pregnancy in women with type 1 diabetes and large for gestational age infants.4
240353092013Developmental programming of growth: genetic variant in GH2 gene encoding placental growth hormone contributes to adult height determination.8
240353092013Developmental programming of growth: genetic variant in GH2 gene encoding placental growth hormone contributes to adult height determination.8
223634002012Maternal and fetal placental growth hormone and IGF axis in type 1 diabetic pregnancy.10
223870442012Differential placental expression profile of human Growth Hormone/Chorionic Somatomammotropin genes in pregnancies with pre-eclampsia and gestational diabetes mellitus.14
224896242012Maternal serum placental growth hormone at 11-13 weeks' gestation in pregnancies delivering small for gestational age neonates.5
223634002012Maternal and fetal placental growth hormone and IGF axis in type 1 diabetic pregnancy.10
223870442012Differential placental expression profile of human Growth Hormone/Chorionic Somatomammotropin genes in pregnancies with pre-eclampsia and gestational diabetes mellitus.14
224896242012Maternal serum placental growth hormone at 11-13 weeks' gestation in pregnancies delivering small for gestational age neonates.5
200059262010hGH-V gene expression and promoter activity under glucose and 5-azacytidine (5azaC) effects.2
204033542010A population-based study of IGF axis polymorphisms and the esophageal inflammation, metaplasia, adenocarcinoma sequence.35
200059262010hGH-V gene expression and promoter activity under glucose and 5-azacytidine (5azaC) effects.2
204033542010A population-based study of IGF axis polymorphisms and the esophageal inflammation, metaplasia, adenocarcinoma sequence.35
198449412009Placental growth hormone and growth hormone binding protein are first trimester maternal serum markers of Down syndrome.4

Citation

Dessen P

GH2 (growth hormone 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45698/css/lib/meetings/