Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3488
MIM: 146734
HGNC: 5474
Ensembl: ENSG00000115461
Variants:
dbSNP: 3488
ClinVar: 3488
TCGA: ENSG00000115461
COSMIC: IGFBP5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115461 | ENST00000233813 | P24593 |
| ENSG00000115461 | ENST00000233813 | A0A024R433 |
| ENSG00000115461 | ENST00000449583 | C9JXX4 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38159363 | 2024 | Secreted insulin-like growth factor binding protein 5 functions as a tumor suppressor and chemosensitizer through inhibiting insulin-like growth factor 1 receptor/protein kinase B pathway in acute myeloid leukemia. | 0 |
| 38318192 | 2024 | Transcriptional profile of human thymus reveals IGFBP5 is correlated with age-related thymic involution. | 0 |
| 38351010 | 2024 | IGFBP5 is released by senescent cells and is internalized by healthy cells, promoting their senescence through interaction with retinoic receptors. | 3 |
| 38874707 | 2024 | Mir-204-5p alleviates mitochondrial dysfunction by targeting IGFBP5 in diabetic cataract. | 0 |
| 38886900 | 2024 | Deletion of endothelial IGFBP5 protects against ischaemic hindlimb injury by promoting angiogenesis. | 1 |
| 38159363 | 2024 | Secreted insulin-like growth factor binding protein 5 functions as a tumor suppressor and chemosensitizer through inhibiting insulin-like growth factor 1 receptor/protein kinase B pathway in acute myeloid leukemia. | 0 |
| 38318192 | 2024 | Transcriptional profile of human thymus reveals IGFBP5 is correlated with age-related thymic involution. | 0 |
| 38351010 | 2024 | IGFBP5 is released by senescent cells and is internalized by healthy cells, promoting their senescence through interaction with retinoic receptors. | 3 |
| 38874707 | 2024 | Mir-204-5p alleviates mitochondrial dysfunction by targeting IGFBP5 in diabetic cataract. | 0 |
| 38886900 | 2024 | Deletion of endothelial IGFBP5 protects against ischaemic hindlimb injury by promoting angiogenesis. | 1 |
| 36918335 | 2023 | Circ_0008450 regulates keloid-derived fibroblast proliferation, migration, invasion and apoptosis with increased IGFBP5 through sponging miR-1224-5p. | 0 |
| 36949068 | 2023 | IGFBP5 is an ROR1 ligand promoting glioblastoma invasion via ROR1/HER2-CREB signaling axis. | 3 |
| 36918335 | 2023 | Circ_0008450 regulates keloid-derived fibroblast proliferation, migration, invasion and apoptosis with increased IGFBP5 through sponging miR-1224-5p. | 0 |
| 36949068 | 2023 | IGFBP5 is an ROR1 ligand promoting glioblastoma invasion via ROR1/HER2-CREB signaling axis. | 3 |
| 34822133 | 2022 | Overexpression of long noncoding RNA MCM3AP-AS1 promotes osteogenic differentiation of dental pulp stem cells via miR-143-3p/IGFBP5 axis. | 4 |
Citation
Dessen P
IGFBP5 (insulin like growth factor binding protein 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45717/igfbp5
