OR51E1 (olfactory receptor family 51 subfamily E member 1)

2007-02-01  

Identity

HGNC
OR51E1
LOCATION
11p15.4
LOCUSID
143503
ALIAS
D-GPCR,DGPCR,GPR136,GPR164,OR51E1P,OR52A3P,POGR,PSGR2

Other Information

Locus ID:

NCBI: 143503
MIM: 611267
HGNC: 15194
Ensembl: ENSG00000180785

Variants:

dbSNP: 143503
ClinVar: 143503
TCGA: ENSG00000180785
COSMIC: OR51E1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000180785ENST00000396952Q8TCB6
ENSG00000180785ENST00000396952A0A126GVF8
ENSG00000180785ENST00000530215E9PKL6

Expression (GTEx)

0
1
2
3
4
5
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Olfactory transductionKEGGko04740
Olfactory transductionKEGGhsa04740
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
Olfactory Signaling PathwayREACTOMER-HSA-381753

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
372078262023Effect of OR51E1 single nucleotide polymorphisms on glioma susceptibility in the Chinese Han population.0
372078262023Effect of OR51E1 single nucleotide polymorphisms on glioma susceptibility in the Chinese Han population.0
336404522021Ectopically expressed olfactory receptors OR51E1 and OR51E2 suppress proliferation and promote cell death in a prostate cancer cell line.11
336404522021Ectopically expressed olfactory receptors OR51E1 and OR51E2 suppress proliferation and promote cell death in a prostate cancer cell line.11
281165192017Medium-chain fatty acids modulate myocardial function via a cardiac odorant receptor.47
281165192017Medium-chain fatty acids modulate myocardial function via a cardiac odorant receptor.47
273740832016The activation of OR51E1 causes growth suppression of human prostate cancer cells.32
273740832016The activation of OR51E1 causes growth suppression of human prostate cancer cells.32
231849102013Olfactory receptor 51E1 protein as a potential novel tissue biomarker for small intestine neuroendocrine carcinomas.35
239699812013Olfactory receptor 51E1 as a novel target for diagnosis in somatostatin receptor-negative lung carcinoids.28
231849102013Olfactory receptor 51E1 protein as a potential novel tissue biomarker for small intestine neuroendocrine carcinomas.35
239699812013Olfactory receptor 51E1 as a novel target for diagnosis in somatostatin receptor-negative lung carcinoids.28
162062862006PSGR2, a novel G-protein coupled receptor, is overexpressed in human prostate cancer.36
164914802006The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase.29
162062862006PSGR2, a novel G-protein coupled receptor, is overexpressed in human prostate cancer.36

Citation

Dessen P

OR51E1 (olfactory receptor family 51 subfamily E member 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45731