Identity
HGNC
LOCATION
1q42.2
LOCUSID
ALIAS
ANHU,SERPINA8,hFLT1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 183
MIM: 106150
HGNC: 333
Ensembl: ENSG00000135744
Variants:
dbSNP: 183
ClinVar: 183
TCGA: ENSG00000135744
COSMIC: AGT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000135744 | ENST00000366667 | P01019 |
| ENSG00000135744 | ENST00000366667 | B0ZBE2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164712308 | Ace Inhibitors, Plain | Chemical | ClinicalAnnotation | associated | PD | 14643574 | |
| PA164712462 | Antiinflammatory agents, non-steroids | Chemical | ClinicalAnnotation | associated | PD | 20538124 | |
| PA165108401 | Acute coronary syndrome | Disease | ClinicalAnnotation | associated | PD | 20538124 | |
| PA443796 | Coronary Artery Disease | Disease | ClinicalAnnotation | associated | PD | 11849656 | |
| PA444552 | Hypertension | Disease | ClinicalAnnotation | associated | PD | 11593098, 14643574, 14700505, 15614026, 17261659, 25143324 | |
| PA446479 | Hypertrophy, Left Ventricular | Disease | ClinicalAnnotation | associated | PD | 11593098, 14700505, 15614026 | |
| PA448388 | amlodipine | Chemical | ClinicalAnnotation | associated | PD | ||
| PA448497 | aspirin | Chemical | ClinicalAnnotation | associated | PD | 20824505 | |
| PA448499 | atenolol | Chemical | ClinicalAnnotation | associated | PD | 11593098, 14700505 | |
| PA448561 | benazepril | Chemical | ClinicalAnnotation | associated | PD | 17261659, 25143324 | |
| PA448970 | chlorthalidone | Chemical | ClinicalAnnotation | associated | PD | ||
| PA450084 | irbesartan | Chemical | ClinicalAnnotation | associated | PD | 11593098, 14700505, 15614026 | |
| PA450242 | lisinopril | Chemical | ClinicalAnnotation | associated | PD | ||
| PA451205 | quinapril | Chemical | ClinicalAnnotation | associated | PD | 11849656 | |
| PA452640 | imidapril | Chemical | ClinicalAnnotation | associated | PD | 25143324 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37909169 | 2024 | Deficiency of Complement C3a and C5a receptors Does Not Prevent Angiotensin II-Induced Hypertension and Hypertensive End-Organ Damage. | 1 |
| 38061470 | 2024 | The role of angiotensin II activation of yes-associated protein/PDZ-binding motif signaling in hypertensive cardiac and vascular remodeling. | 0 |
| 38105755 | 2024 | OTUD6A in tubular epithelial cells mediates angiotensin II-induced kidney injury by targeting STAT3. | 0 |
| 38265173 | 2024 | Correlation of single nucleotide polymorphisms in the AGT gene with susceptibility to systemic lupus erythematosus in Northeast China. | 0 |
| 38279313 | 2024 | Interplay of Angiotensin Peptides, Vasopressin, and Insulin in the Heart: Experimental and Clinical Evidence of Altered Interactions in Obesity and Diabetes Mellitus. | 0 |
| 38380450 | 2024 | Genetic Variations of Angiotensinogen, Angiotensin Converting Enzyme, and Angiotensin Type 1 Receptor with the Risk of Pulmonary Tuberculosis. | 0 |
| 38489704 | 2024 | Association of rs5051 and rs699 polymorphisms in angiotensinogen with coronary artery disease in Iranian population: A case-control study. | 0 |
| 38492325 | 2024 | Role of Angiotensin II in Non-Alcoholic Steatosis Development. | 0 |
| 38622720 | 2024 | The role of the brain renin-angiotensin system in Parkinson´s disease. | 1 |
| 37909169 | 2024 | Deficiency of Complement C3a and C5a receptors Does Not Prevent Angiotensin II-Induced Hypertension and Hypertensive End-Organ Damage. | 1 |
| 38061470 | 2024 | The role of angiotensin II activation of yes-associated protein/PDZ-binding motif signaling in hypertensive cardiac and vascular remodeling. | 0 |
| 38105755 | 2024 | OTUD6A in tubular epithelial cells mediates angiotensin II-induced kidney injury by targeting STAT3. | 0 |
| 38265173 | 2024 | Correlation of single nucleotide polymorphisms in the AGT gene with susceptibility to systemic lupus erythematosus in Northeast China. | 0 |
| 38279313 | 2024 | Interplay of Angiotensin Peptides, Vasopressin, and Insulin in the Heart: Experimental and Clinical Evidence of Altered Interactions in Obesity and Diabetes Mellitus. | 0 |
| 38380450 | 2024 | Genetic Variations of Angiotensinogen, Angiotensin Converting Enzyme, and Angiotensin Type 1 Receptor with the Risk of Pulmonary Tuberculosis. | 0 |
Citation
Dessen P
AGT (angiotensinogen)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45772/agt
