Identity
HGNC
LOCATION
16q22.1
LOCUSID
ALIAS
AME,AME1,HSD11K,HSD2,SDR9C3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3291
MIM: 614232
HGNC: 5209
Ensembl: ENSG00000176387
Variants:
dbSNP: 3291
ClinVar: 3291
TCGA: ENSG00000176387
COSMIC: HSD11B2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000176387 | ENST00000326152 | P80365 |
| ENSG00000176387 | ENST00000566606 | R4GN04 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38814727 | 2024 | DNA methylation-mediated 11βHSD2 downregulation drives the increases in angiotensin-converting enzyme and angiotensin II within preeclamptic placentas. | 0 |
| 38814727 | 2024 | DNA methylation-mediated 11βHSD2 downregulation drives the increases in angiotensin-converting enzyme and angiotensin II within preeclamptic placentas. | 0 |
| 37130784 | 2023 | Down-Regulation of the Mineralocorticoid Receptor (MR) and Up-Regulation of Hydroxysteroid 11-Beta Dehydrogenase Type 2 (HSD11B2) Isoenzyme in Critically Ill Patients. | 0 |
| 37130784 | 2023 | Down-Regulation of the Mineralocorticoid Receptor (MR) and Up-Regulation of Hydroxysteroid 11-Beta Dehydrogenase Type 2 (HSD11B2) Isoenzyme in Critically Ill Patients. | 0 |
| 35735229 | 2022 | Long noncoding RNA PVT1 accelerates the growth of placental trophoblasts in preeclampsia through the microRNA-24-3p/HSD11B2 axis. | 0 |
| 35735229 | 2022 | Long noncoding RNA PVT1 accelerates the growth of placental trophoblasts in preeclampsia through the microRNA-24-3p/HSD11B2 axis. | 0 |
| 33621325 | 2021 | Rhythm of Fetoplacental 11β-Hydroxysteroid Dehydrogenase Type 2 - Fetal Protection From Morning Maternal Glucocorticoids. | 3 |
| 34497581 | 2021 | Detection of Urinary Exosomal HSD11B2 mRNA Expression: A Useful Novel Tool for the Diagnostic Approach of Dysfunctional 11β-HSD2-Related Hypertension. | 2 |
| 33621325 | 2021 | Rhythm of Fetoplacental 11β-Hydroxysteroid Dehydrogenase Type 2 - Fetal Protection From Morning Maternal Glucocorticoids. | 3 |
| 34497581 | 2021 | Detection of Urinary Exosomal HSD11B2 mRNA Expression: A Useful Novel Tool for the Diagnostic Approach of Dysfunctional 11β-HSD2-Related Hypertension. | 2 |
| 31813102 | 2020 | Cortisol and 11 beta-hydroxysteroid dehydrogenase type 2 as potential determinants of renal citrate excretion in healthy children. | 1 |
| 32187412 | 2020 | Association among placental 11β-HSD2, PPAR-γ, and NF-κB p65 in small-for-gestational-age infants: A nested case-control study. | 1 |
| 32853845 | 2020 | Placental 11β-HSD2 downregulated in HIV associated preeclampsia. | 3 |
| 33098869 | 2020 | Chinese herbal medicine promote tissue differentiation in colorectal cancer by activating HSD11B2. | 5 |
| 33238679 | 2020 | [Genetic expression differences of 11 beta-hydroxysteroid dehydrogenase in the bone microvascular endothelial cells derived from different regions of the human femoral head]. | 0 |
Citation
Dessen P
HSD11B2 (hydroxysteroid 11-beta dehydrogenase 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45783/hsd11b2
