JDP2 (Jun dimerization protein 2)

2007-02-01  

Identity

HGNC
LOCATION
14q24.3
LOCUSID
ALIAS
JUNDM2
FUSION GENES

Other Information

Locus ID:

NCBI: 122953
MIM: 608657
HGNC: 17546
Ensembl: ENSG00000140044

Variants:

dbSNP: 122953
ClinVar: 122953
TCGA: ENSG00000140044
COSMIC: JDP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140044ENST00000267569Q8WYK2
ENSG00000140044ENST00000419727Q8WYK2
ENSG00000140044ENST00000419727A0A024R6D7
ENSG00000140044ENST00000435893Q8WYK2
ENSG00000140044ENST00000435893A0A024R6D7
ENSG00000140044ENST00000437176Q8WYK2
ENSG00000140044ENST00000437176A0A024R6D7
ENSG00000140044ENST00000559060H0YKE4
ENSG00000140044ENST00000651602Q8WYK2
ENSG00000140044ENST00000651602A0A024R6D7

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA283MAPK8GenePathwayassociated23922006
PA30621MAPK14GenePathwayassociated23922006

References

Pubmed IDYearTitleCitations
371791252023Palmitic acid-induced microRNA-143-5p expression promotes the epithelial-mesenchymal transition of retinal pigment epithelium via negatively regulating JDP2.0
371791252023Palmitic acid-induced microRNA-143-5p expression promotes the epithelial-mesenchymal transition of retinal pigment epithelium via negatively regulating JDP2.0
321503332020Down-regulated lncRNA AGAP2-AS1 contributes to pre-eclampsia as a competing endogenous RNA for JDP2 by impairing trophoblastic phenotype.14
331087042020JDP2 is directly regulated by ATF4 and modulates TRAIL sensitivity by suppressing the ATF4-DR5 axis.4
321503332020Down-regulated lncRNA AGAP2-AS1 contributes to pre-eclampsia as a competing endogenous RNA for JDP2 by impairing trophoblastic phenotype.14
331087042020JDP2 is directly regulated by ATF4 and modulates TRAIL sensitivity by suppressing the ATF4-DR5 axis.4
307213352019Using PU.1 and Jun dimerization protein 2 transcription factor expression in myelodysplastic syndromes to predict treatment response and leukaemia transformation.3
308776242019miR-501 acts as an independent prognostic factor that promotes the epithelial-mesenchymal transition through targeting JDP2 in hepatocellular carcinoma.7
307213352019Using PU.1 and Jun dimerization protein 2 transcription factor expression in myelodysplastic syndromes to predict treatment response and leukaemia transformation.3
308776242019miR-501 acts as an independent prognostic factor that promotes the epithelial-mesenchymal transition through targeting JDP2 in hepatocellular carcinoma.7
299415492018JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia.14
299415492018JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia.14
283154252017The expression of a tumor suppressor gene JDP2 and its prognostic value in hepatocellular carcinoma patients.6
283154252017The expression of a tumor suppressor gene JDP2 and its prognostic value in hepatocellular carcinoma patients.6
241203782013Preeclamptic plasma induces transcription modifications involving the AP-1 transcriptional regulator JDP2 in endothelial cells.10

Citation

Dessen P

JDP2 (Jun dimerization protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45799/jdp2