IGHD (immunoglobulin heavy constant delta)

2007-02-01 Affiliation

Identity

HGNC

IGHD

LOCATION

14q32.33

LOCUSID

3495

ALIAS

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 3495
MIM: 147170
HGNC: 5480
Ensembl: ENSG00000211898
IMGT/GENE-DB:

Variants:

dbSNP: 3495
ClinVar: 3495
TCGA: ENSG00000211898
COSMIC: IGHD

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000211898	ENST00000390556	A0A0A0MS09
ENSG00000211898	ENST00000613640	P01880

Expression (GTEx)

100

150

200

250

300

350

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
30291028	2018	Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44.	32
30291028	2018	Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44.	32
28958373	2017	Expression of immunoglobulin D is increased in chronic rhinosinusitis.	5
28958373	2017	Expression of immunoglobulin D is increased in chronic rhinosinusitis.	5
17169423	2007	Use of IGHJ and IGHD gene mutations in analysis of immunoglobulin sequences for the prognosis of chronic lymphocytic leukemia.	6
17475860	2007	Characterization of the IgD binding site of encapsulated Haemophilus influenzae serotype b.	3
17169423	2007	Use of IGHJ and IGHD gene mutations in analysis of immunoglobulin sequences for the prognosis of chronic lymphocytic leukemia.	6
17475860	2007	Characterization of the IgD binding site of encapsulated Haemophilus influenzae serotype b.	3
16402215	2006	Reconsidering the human immunoglobulin heavy-chain locus: 1. An evaluation of the expressed human IGHD gene repertoire.	9
16402215	2006	Reconsidering the human immunoglobulin heavy-chain locus: 1. An evaluation of the expressed human IGHD gene repertoire.	9
11902141	2002	Role of surface IgM and IgD on survival of the cells from B-cell chronic lymphocytic leukemia.	5
12023968	2002	The role of constant region carbohydrate in the assembly and secretion of human IgD and IgA1.	18
11902141	2002	Role of surface IgM and IgD on survival of the cells from B-cell chronic lymphocytic leukemia.	5
12023968	2002	The role of constant region carbohydrate in the assembly and secretion of human IgD and IgA1.	18
8418208	1993	Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells.	55

Citation

Dessen P

IGHD (immunoglobulin heavy constant delta)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45806