Identity
HGNC
LOCATION
5q21.1
LOCUSID
ALIAS
PST,PST1,SIAT8D,ST8SIA-IV
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7903
MIM: 602547
HGNC: 10871
Ensembl: ENSG00000113532
Variants:
dbSNP: 7903
ClinVar: 7903
TCGA: ENSG00000113532
COSMIC: ST8SIA4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000113532 | ENST00000231461 | Q92187 |
| ENSG00000113532 | ENST00000451528 | Q92187 |
| ENSG00000113532 | ENST00000523381 | E5RFK3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38103644 | 2024 | Identification of a buried β-strand as a novel disease-related motif in the human polysialyltransferases. | 0 |
| 38103644 | 2024 | Identification of a buried β-strand as a novel disease-related motif in the human polysialyltransferases. | 0 |
| 28233978 | 2017 | The Polybasic Region of the Polysialyltransferase ST8Sia-IV Binds Directly to the Neural Cell Adhesion Molecule, NCAM. | 10 |
| 28427206 | 2017 | miR-146a and miR-146b promote proliferation, migration and invasion of follicular thyroid carcinoma via inhibition of ST8SIA4. | 22 |
| 28810663 | 2017 | Different properties of polysialic acids synthesized by the polysialyltransferases ST8SIA2 and ST8SIA4. | 9 |
| 28233978 | 2017 | The Polybasic Region of the Polysialyltransferase ST8Sia-IV Binds Directly to the Neural Cell Adhesion Molecule, NCAM. | 10 |
| 28427206 | 2017 | miR-146a and miR-146b promote proliferation, migration and invasion of follicular thyroid carcinoma via inhibition of ST8SIA4. | 22 |
| 28810663 | 2017 | Different properties of polysialic acids synthesized by the polysialyltransferases ST8SIA2 and ST8SIA4. | 9 |
| 26884342 | 2016 | Sequence Requirements for Neuropilin-2 Recognition by ST8SiaIV and Polysialylation of Its O-Glycans. | 13 |
| 27074314 | 2016 | ST8SIA4-Dependent Polysialylation is Part of a Developmental Program Required for Germ Layer Formation from Human Pluripotent Stem Cells. | 15 |
| 27527856 | 2016 | Upregulation of miR-181c inhibits chemoresistance by targeting ST8SIA4 in chronic myelocytic leukemia. | 22 |
| 28032858 | 2016 | Functional roles of sialylation in breast cancer progression through miR-26a/26b targeting ST8SIA4. | 33 |
| 26884342 | 2016 | Sequence Requirements for Neuropilin-2 Recognition by ST8SiaIV and Polysialylation of Its O-Glycans. | 13 |
| 27074314 | 2016 | ST8SIA4-Dependent Polysialylation is Part of a Developmental Program Required for Germ Layer Formation from Human Pluripotent Stem Cells. | 15 |
| 27527856 | 2016 | Upregulation of miR-181c inhibits chemoresistance by targeting ST8SIA4 in chronic myelocytic leukemia. | 22 |
Citation
Dessen P
ST8SIA4 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45830/st8sia4
