Identity
HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
CaI-PLA2,GVI,INAD1,IPLA2-VIA,NBIA2,NBIA2A,NBIA2B,PARK14,PLA2,PNPLA9,iPLA2,iPLA2beta
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8398
MIM: 603604
HGNC: 9039
Ensembl: ENSG00000184381
Variants:
dbSNP: 8398
ClinVar: 8398
TCGA: ENSG00000184381
COSMIC: PLA2G6
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA449552 | etoposide | Chemical | MultilinkAnnotation | associated | 24444404 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36990122 | 2023 | Molecular basis of unique specificity and regulation of group VIA calcium-independent phospholipase A(2) (PNPLA9) and its role in neurodegenerative diseases. | 1 |
| 37139542 | 2023 | PLA2G6-associated late-onset parkinsonism in a Sudanese family. | 0 |
| 37236368 | 2023 | The role of the PLA2G6 gene in neurodegenerative diseases. | 3 |
| 37290257 | 2023 | Association between PLA2 gene polymorphisms and treatment response to antipsychotic medications: A study of antipsychotic-naïve first-episode psychosis patients and nonadherent chronic psychosis patients. | 0 |
| 37403138 | 2023 | Phenotype and genotype heterogeneity of PLA2G6-associated neurodegeneration in a cohort of pediatric and adult patients. | 0 |
| 36990122 | 2023 | Molecular basis of unique specificity and regulation of group VIA calcium-independent phospholipase A(2) (PNPLA9) and its role in neurodegenerative diseases. | 1 |
| 37139542 | 2023 | PLA2G6-associated late-onset parkinsonism in a Sudanese family. | 0 |
| 37236368 | 2023 | The role of the PLA2G6 gene in neurodegenerative diseases. | 3 |
| 37290257 | 2023 | Association between PLA2 gene polymorphisms and treatment response to antipsychotic medications: A study of antipsychotic-naïve first-episode psychosis patients and nonadherent chronic psychosis patients. | 0 |
| 37403138 | 2023 | Phenotype and genotype heterogeneity of PLA2G6-associated neurodegeneration in a cohort of pediatric and adult patients. | 0 |
| 34622992 | 2022 | Dissecting the Phenotype and Genotype of PLA2G6-Related Parkinsonism. | 14 |
| 35092705 | 2022 | Novel insertion mutation in the PLA2G6 gene in an Iranian family with infantile neuroaxonal dystrophy. | 2 |
| 35247231 | 2022 | Genome sequencing reveals novel noncoding variants in PLA2G6 and LMNB1 causing progressive neurologic disease. | 3 |
| 34622992 | 2022 | Dissecting the Phenotype and Genotype of PLA2G6-Related Parkinsonism. | 14 |
| 35092705 | 2022 | Novel insertion mutation in the PLA2G6 gene in an Iranian family with infantile neuroaxonal dystrophy. | 2 |
Citation
Dessen P
PLA2G6 (phospholipase A2 group VI)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45836/pla2g6
