DNALI1 (dynein axonemal light intermediate chain 1)

2007-02-01  

Identity

HGNC
DNALI1
LOCATION
1p34.3
LOCUSID
7802
ALIAS
P28,dJ423B22.5,hp28
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7802
MIM: 602135
HGNC: 14353
Ensembl: ENSG00000163879

Variants:

dbSNP: 7802
ClinVar: 7802
TCGA: ENSG00000163879
COSMIC: DNALI1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163879ENST00000296218A0A499FIY3
ENSG00000163879ENST00000652629O14645

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Huntington's diseaseKEGGko05016
Huntington's diseaseKEGGhsa05016

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383485402024DNALI1 Promotes Neurodegeneration after Traumatic Brain Injury via Inhibition of Autophagosome-Lysosome Fusion.1
383485402024DNALI1 Promotes Neurodegeneration after Traumatic Brain Injury via Inhibition of Autophagosome-Lysosome Fusion.1
367925882023DNALI1 deficiency causes male infertility with severe asthenozoospermia in humans and mice by disrupting the assembly of the flagellar inner dynein arms and fibrous sheath.11
379550802023DNALI1 is a prognosis-related biomarker and correlates with immune infiltrates in low grade glioma.0
367925882023DNALI1 deficiency causes male infertility with severe asthenozoospermia in humans and mice by disrupting the assembly of the flagellar inner dynein arms and fibrous sheath.11
379550802023DNALI1 is a prognosis-related biomarker and correlates with immune infiltrates in low grade glioma.0
295283772018Identification of a novel host protein interacting with Toxoplasma gondii toxofilin via a yeast two-hybrid system.0
295283772018Identification of a novel host protein interacting with Toxoplasma gondii toxofilin via a yeast two-hybrid system.0
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
169904352006Recruitment of dynein to the Jurkat immunological synapse.108
169904352006Recruitment of dynein to the Jurkat immunological synapse.108

Citation

Dessen P

DNALI1 (dynein axonemal light intermediate chain 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45844/favicon/gene-fusions/deep-insight-explorer/