Identity
HGNC
LOCATION
21q21.3
LOCUSID
ALIAS
E4TF1-60,E4TF1A,NFT2,NRF2,NRF2A,RCH04A07
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2551
MIM: 600609
HGNC: 4071
Ensembl: ENSG00000154727
Variants:
dbSNP: 2551
ClinVar: 2551
TCGA: ENSG00000154727
COSMIC: GABPA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000154727 | ENST00000354828 | Q06546 |
| ENSG00000154727 | ENST00000354828 | A8IE48 |
| ENSG00000154727 | ENST00000400075 | Q06546 |
| ENSG00000154727 | ENST00000400075 | A8IE48 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35549739 | 2022 | GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma. | 8 |
| 35549739 | 2022 | GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma. | 8 |
| 34306255 | 2021 | GABPA Expression in Endometrial Carcinoma: A Prognostic Marker. | 4 |
| 34306255 | 2021 | GABPA Expression in Endometrial Carcinoma: A Prognostic Marker. | 4 |
| 32768523 | 2020 | TERT promoter mutations and GABP transcription factors in carcinogenesis: More foes than friends. | 23 |
| 32768523 | 2020 | TERT promoter mutations and GABP transcription factors in carcinogenesis: More foes than friends. | 23 |
| 30181547 | 2019 | GABPA inhibits invasion/metastasis in papillary thyroid carcinoma by regulating DICER1 expression. | 30 |
| 30836589 | 2019 | Identification of GA-Binding Protein Transcription Factor Alpha Subunit (GABPA) as a Novel Bookmarking Factor. | 5 |
| 30181547 | 2019 | GABPA inhibits invasion/metastasis in papillary thyroid carcinoma by regulating DICER1 expression. | 30 |
| 30836589 | 2019 | Identification of GA-Binding Protein Transcription Factor Alpha Subunit (GABPA) as a Novel Bookmarking Factor. | 5 |
| 29118074 | 2018 | Golgi stress-induced transcriptional changes mediated by MAPK signaling and three ETS transcription factors regulate MCL1 splicing. | 19 |
| 29413900 | 2018 | Expression of the human TIMM23 and TIMM23B genes is regulated by the GABP transcription factor. | 3 |
| 29118074 | 2018 | Golgi stress-induced transcriptional changes mediated by MAPK signaling and three ETS transcription factors regulate MCL1 splicing. | 19 |
| 29413900 | 2018 | Expression of the human TIMM23 and TIMM23B genes is regulated by the GABP transcription factor. | 3 |
| 28108517 | 2017 | SDHD Promoter Mutations Ablate GABP Transcription Factor Binding in Melanoma. | 7 |
Citation
Dessen P
GABPA (GA binding protein transcription factor subunit alpha)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45863/gabpa
