Identity
HGNC
LOCATION
6q23.2
LOCUSID
ALIAS
ARHR2,COLED,M6S1,NPP1,NPPS,PC-1,PCA1,PDNP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5167
MIM: 173335
HGNC: 3356
Ensembl: ENSG00000197594
Variants:
dbSNP: 5167
ClinVar: 5167
TCGA: ENSG00000197594
COSMIC: ENPP1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37871131 | 2024 | ENPP1 in Blood and Bone: Skeletal and Soft Tissue Diseases Induced by ENPP1 Deficiency. | 1 |
| 38142838 | 2024 | Targeting ENPP1 for cancer immunotherapy: Killing two birds with one stone. | 1 |
| 38265511 | 2024 | ENPP1 inhibits the transcription activity of the hepatitis B virus pregenomic promoter by upregulating the acetylation of LMNB1. | 0 |
| 38582229 | 2024 | TET3 boosts hepatocyte autophagy and impairs non-alcoholic fatty liver disease by increasing ENPP1 promoter hypomethylation. | 0 |
| 38806089 | 2024 | Quantitative correlation of ENPP1 pathogenic variants with disease phenotype. | 0 |
| 37871131 | 2024 | ENPP1 in Blood and Bone: Skeletal and Soft Tissue Diseases Induced by ENPP1 Deficiency. | 1 |
| 38142838 | 2024 | Targeting ENPP1 for cancer immunotherapy: Killing two birds with one stone. | 1 |
| 38265511 | 2024 | ENPP1 inhibits the transcription activity of the hepatitis B virus pregenomic promoter by upregulating the acetylation of LMNB1. | 0 |
| 38582229 | 2024 | TET3 boosts hepatocyte autophagy and impairs non-alcoholic fatty liver disease by increasing ENPP1 promoter hypomethylation. | 0 |
| 38806089 | 2024 | Quantitative correlation of ENPP1 pathogenic variants with disease phenotype. | 0 |
| 37003563 | 2023 | Effects of food, fasting, and exercise on plasma pyrophosphate levels and ENPP1 activity in healthy adults. | 0 |
| 37231232 | 2023 | Role of ENPP1 Gene Variants in the Susceptibility to Diabetic Nephropathy in Patients with type 2 Diabetes Mellitus. | 1 |
| 38117852 | 2023 | ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway in breast cancer. | 2 |
| 37003563 | 2023 | Effects of food, fasting, and exercise on plasma pyrophosphate levels and ENPP1 activity in healthy adults. | 0 |
| 37231232 | 2023 | Role of ENPP1 Gene Variants in the Susceptibility to Diabetic Nephropathy in Patients with type 2 Diabetes Mellitus. | 1 |
Citation
Dessen P
ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45867/enpp1
