Identity
HGNC
LOCATION
15q15.1
LOCUSID
ALIAS
IP3-3KA,IP3KA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3706
MIM: 147521
HGNC: 6178
Ensembl: ENSG00000137825
Variants:
dbSNP: 3706
ClinVar: 3706
TCGA: ENSG00000137825
COSMIC: ITPKA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000137825 | ENST00000260386 | P23677 |
| ENSG00000137825 | ENST00000425927 | C9JC74 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36688944 | 2023 | The actin bundling activity of ITPKA mainly accounts for its migration-promoting effect in lung cancer cells. | 1 |
| 37664985 | 2023 | Commentary on: The actin bundling activity of ITPKA mainly accounts for its migration-promoting effect in lung cancer cells. | 0 |
| 36688944 | 2023 | The actin bundling activity of ITPKA mainly accounts for its migration-promoting effect in lung cancer cells. | 1 |
| 37664985 | 2023 | Commentary on: The actin bundling activity of ITPKA mainly accounts for its migration-promoting effect in lung cancer cells. | 0 |
| 33624455 | 2021 | Relationship of ITPKA expression with the prognosis of breast cancer. | 1 |
| 33879633 | 2021 | ITPKA induces cell senescence, inhibits ovarian cancer tumorigenesis and can be downregulated by miR-203. | 2 |
| 33624455 | 2021 | Relationship of ITPKA expression with the prognosis of breast cancer. | 1 |
| 33879633 | 2021 | ITPKA induces cell senescence, inhibits ovarian cancer tumorigenesis and can be downregulated by miR-203. | 2 |
| 32015686 | 2020 | TFAP2A Induced ITPKA Serves as an Oncogene and Interacts with DBN1 in Lung Adenocarcinoma. | 14 |
| 32015686 | 2020 | TFAP2A Induced ITPKA Serves as an Oncogene and Interacts with DBN1 in Lung Adenocarcinoma. | 14 |
| 30466786 | 2019 | PKA-dependent phosphorylation of IP3K-A at Ser119 regulates a binding affinity with EB3. | 1 |
| 30466786 | 2019 | PKA-dependent phosphorylation of IP3K-A at Ser119 regulates a binding affinity with EB3. | 1 |
| 27234602 | 2016 | ITPKA Gene Body Methylation Regulates Gene Expression and Serves as an Early Diagnostic Marker in Lung and Other Cancers. | 28 |
| 27234602 | 2016 | ITPKA Gene Body Methylation Regulates Gene Expression and Serves as an Early Diagnostic Marker in Lung and Other Cancers. | 28 |
| 26249031 | 2015 | ITPKA expression is a novel prognostic factor in hepatocellular carcinoma. | 7 |
Citation
Dessen P
ITPKA (inositol-trisphosphate 3-kinase A)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45875/itpka
