Identity
HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
D6S2245E,FABG,FABGL,H2-KE6,HKE6,KE6,RING2,SDR30C1,dJ1033B10.9
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7923
MIM: 601417
HGNC: 3554
Ensembl: ENSG00000204228
Variants:
dbSNP: 7923
ClinVar: 7923
TCGA: ENSG00000204228
COSMIC: HSD17B8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000204228 | ENST00000374662 | Q92506 |
| ENSG00000204228 | ENST00000374662 | A0A1U9X7U3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35184130 | 2022 | The Obesity-Related Metabolic Gene HSD17B8 Protects Against Breast Cancer: High RNA/Protein Expression Means a Better Prognosis. | 0 |
| 35184130 | 2022 | The Obesity-Related Metabolic Gene HSD17B8 Protects Against Breast Cancer: High RNA/Protein Expression Means a Better Prognosis. | 0 |
| 20214802 | 2010 | Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer. | 11 |
| 20587610 | 2010 | Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. | 3 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20214802 | 2010 | Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer. | 11 |
| 20587610 | 2010 | Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. | 3 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 18852215 | 2009 | Estradiol induces type 8 17beta-hydroxysteroid dehydrogenase expression: crosstalk between estrogen receptor alpha and C/EBPbeta. | 8 |
| 19343046 | 2009 | Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. | 4 |
| 19571038 | 2009 | 17beta-hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS. | 19 |
| 19851445 | 2009 | High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. | 58 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
Citation
Dessen P
HSD17B8 (hydroxysteroid 17-beta dehydrogenase 8)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45893/hsd17b8
