Identity
HGNC
LOCATION
17q12
LOCUSID
ALIAS
DIF-3,DIF3,LCRG1,LZK1,ZFP403,ZNF403
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79893
MIM: 612275
HGNC: 19357
Ensembl: ENSG00000278311
Variants:
dbSNP: 79893
ClinVar: 79893
TCGA: ENSG00000278311
COSMIC: GGNBP2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000278311 | ENST00000611219 | A0A087X0E5 |
| ENSG00000278311 | ENST00000613102 | Q9H3C7 |
| ENSG00000278311 | ENST00000615952 | A0A087X1N0 |
| ENSG00000278311 | ENST00000616019 | A0A087X1D7 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31797427 | 2020 | Effects of gametogenetin-binding protein 2 on proliferation, invasion and migration of prostate cancer PC-3 cells. | 3 |
| 33125130 | 2020 | Effects of zinc finger protein 403 on the proliferation, migration and invasion abilities of prostate cancer cells. | 2 |
| 31797427 | 2020 | Effects of gametogenetin-binding protein 2 on proliferation, invasion and migration of prostate cancer PC-3 cells. | 3 |
| 33125130 | 2020 | Effects of zinc finger protein 403 on the proliferation, migration and invasion abilities of prostate cancer cells. | 2 |
| 30450530 | 2019 | GGNBP2 suppresses triple-negative breast cancer aggressiveness through inhibition of IL-6/STAT3 signaling activation. | 10 |
| 30450530 | 2019 | GGNBP2 suppresses triple-negative breast cancer aggressiveness through inhibition of IL-6/STAT3 signaling activation. | 10 |
| 28864131 | 2017 | ZFP403, a novel tumor suppressor, inhibits the proliferation and metastasis in ovarian cancer. | 9 |
| 28864131 | 2017 | ZFP403, a novel tumor suppressor, inhibits the proliferation and metastasis in ovarian cancer. | 9 |
| 27357812 | 2016 | GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells. | 9 |
| 27357812 | 2016 | GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells. | 9 |
| 24842157 | 2014 | Downregulation of tumor suppressor gene ribonuclease T2 and gametogenetin binding protein 2 is associated with drug resistance in ovarian cancer. | 12 |
| 24842157 | 2014 | Downregulation of tumor suppressor gene ribonuclease T2 and gametogenetin binding protein 2 is associated with drug resistance in ovarian cancer. | 12 |
| 22350815 | 2012 | Knockdown of ZNF403 inhibits cell proliferation and induces G2/M arrest by modulating cell-cycle mediators. | 8 |
| 22350815 | 2012 | Knockdown of ZNF403 inhibits cell proliferation and induces G2/M arrest by modulating cell-cycle mediators. | 8 |
| 15145523 | 2004 | Molecular cloning and characterization of LCRG1 a novel gene localized to the tumor suppressor locus D17S800-D17S930. | 6 |
Citation
Dessen P
GGNBP2 (gametogenetin binding protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45910/ggnbp2
