Identity
HGNC
LOCATION
12p12.1
LOCUSID
ALIAS
BCATC,BCT1,ECA39,MECA39,PNAS121,PP18
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 586
MIM: 113520
HGNC: 976
Ensembl: ENSG00000060982
Variants:
dbSNP: 586
ClinVar: 586
TCGA: ENSG00000060982
COSMIC: BCAT1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37769206 | 2024 | Branched-chain amino acid transaminase 1 regulates glioblastoma cell plasticity and contributes to immunosuppression. | 0 |
| 38309289 | 2024 | Integrated single-cell and bulk characterization of branched chain amino acid metabolism-related key gene BCAT1 and association with prognosis and immunogenicity of clear cell renal cell carcinoma. | 0 |
| 38340163 | 2024 | High expression of BCAT1 sensitizes AML cells to PARP inhibitor by suppressing DNA damage response. | 0 |
| 38369471 | 2024 | HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT1. | 0 |
| 37769206 | 2024 | Branched-chain amino acid transaminase 1 regulates glioblastoma cell plasticity and contributes to immunosuppression. | 0 |
| 38309289 | 2024 | Integrated single-cell and bulk characterization of branched chain amino acid metabolism-related key gene BCAT1 and association with prognosis and immunogenicity of clear cell renal cell carcinoma. | 0 |
| 38340163 | 2024 | High expression of BCAT1 sensitizes AML cells to PARP inhibitor by suppressing DNA damage response. | 0 |
| 38369471 | 2024 | HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT1. | 0 |
| 36344754 | 2023 | BCAT1, as a prognostic factor for HCC, can promote the development of liver cancer through activation of the AKT signaling pathway and EMT. | 5 |
| 36344754 | 2023 | BCAT1, as a prognostic factor for HCC, can promote the development of liver cancer through activation of the AKT signaling pathway and EMT. | 5 |
| 34984849 | 2022 | BCAT1: A risk factor in multiple cancers based on a pan-cancer analysis. | 14 |
| 35290664 | 2022 | Detection of recurrent colorectal cancer with high specificity using a reporting threshold for circulating tumor DNA methylated in BCAT1 and IKZF1. | 6 |
| 36111572 | 2022 | BCAT1 promotes lung adenocarcinoma progression through enhanced mitochondrial function and NF-κB pathway activation. | 2 |
| 36123616 | 2022 | Translation of a tissue epigenetic signature to circulating free DNA suggests BCAT1 as a potential noninvasive diagnostic biomarker for lung cancer. | 4 |
| 36260995 | 2022 | BCAT1 redox function maintains mitotic fidelity. | 5 |
Citation
Dessen P
BCAT1 (branched chain amino acid transaminase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45917/bcat1
