Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56253
MIM: 612597
HGNC: 24313
Ensembl: ENSG00000109943
Variants:
dbSNP: 56253
ClinVar: 56253
TCGA: ENSG00000109943
COSMIC: CRTAM
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000109943 | ENST00000227348 | O95727 |
| ENSG00000109943 | ENST00000533709 | O95727 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Adaptive Immune System | REACTOME | R-HSA-1280218 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | REACTOME | R-HSA-198933 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38354509 | 2024 | CRTAM promotes antitumor immune response in triple negative breast cancer by enhancing CD8+ T cell infiltration. | 0 |
| 38354509 | 2024 | CRTAM promotes antitumor immune response in triple negative breast cancer by enhancing CD8+ T cell infiltration. | 0 |
| 32300914 | 2020 | Prokaryotic Expression of the Immunoglobulin's Domains of CRTAM to Characterize a Monoclonal Antibody. | 1 |
| 32300914 | 2020 | Prokaryotic Expression of the Immunoglobulin's Domains of CRTAM to Characterize a Monoclonal Antibody. | 1 |
| 30791148 | 2019 | CRTAM(+) NK cells endowed with suppressor properties arise in leukemic bone marrow. | 7 |
| 30791148 | 2019 | CRTAM(+) NK cells endowed with suppressor properties arise in leukemic bone marrow. | 7 |
| 26694968 | 2016 | CRTAM determines the CD4+ cytotoxic T lymphocyte lineage. | 91 |
| 26694968 | 2016 | CRTAM determines the CD4+ cytotoxic T lymphocyte lineage. | 91 |
| 25910959 | 2015 | CRTAM is negatively regulated by ZEB1 in T cells. | 5 |
| 25910959 | 2015 | CRTAM is negatively regulated by ZEB1 in T cells. | 5 |
| 23530148 | 2013 | CRTAM receptor engagement by Necl-2 on tumor cells triggers cell death of activated Vγ9Vδ2 T cells. | 7 |
| 23827383 | 2013 | A genome-wide association study for malignant mesothelioma risk. | 18 |
| 23871486 | 2013 | Competition of cell adhesion and immune recognition: insights into the interaction between CRTAM and nectin-like 2. | 6 |
| 23530148 | 2013 | CRTAM receptor engagement by Necl-2 on tumor cells triggers cell death of activated Vγ9Vδ2 T cells. | 7 |
| 23827383 | 2013 | A genome-wide association study for malignant mesothelioma risk. | 18 |
Citation
Dessen P
CRTAM (cytotoxic and regulatory T cell molecule)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45934/crtam
